Head and Neck Lymphomas in HIV Patients: a Clinical Perspective

Overview

Journal Int Arch Otorhinolaryngol

Publisher Thieme

Specialty Otorhinolaryngology

Date 2017 Oct 12

PMID 29018505

Citations 5

Authors

Natsuki Oishi

Jose Vicente Bagan

Karla Javier

Enrique Zapater

Affiliations

Soon will be listed here.

Abstract

Because of the many HIV-related malignancies, the diagnosis and treatment of lymphoma in patients infected with human immunodeficiency virus are challenging. Here, we review current knowledge of the pathogenesis, epidemiology, symptomatology, diagnosis, and treatment of head and neck lymphomas in HIV patients from a clinical perspective. Although Hodgkin's lymphoma is not an AIDS-defining neoplasm, its prevalence is ten times higher in HIV patients than in the general population. NHL is the second most common malignancy in HIV patients, after Kaposi's sarcoma. In this group of patients, NHL is characterized by rapid progression, frequent extranodal involvement, and a poor outcome. HIV-related salivary gland disease is a benign condition that shares some features with lymphomas and is considered in their differential diagnosis. The otolaryngologist may be the first clinician to diagnose head and neck lymphomas. The increasing survival of HIV patients implies clinical and epidemiological changes in the behavior of this disease. Early diagnosis is important to improve the prognosis and avoid the propagation of HIV infection.

Citing Articles

Extra-Nodal Lymphomas of the Head and Neck and Oral Cavity: A Retrospective Study.

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[Spinal cord compression secondary to metastasis of gingival Burkitt lymphoma revealing a case of HIV infection in Morocco].

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Diagnostic Interval in Extranodal Non-Hodgkin Head and Neck Lymphomas.

Castro A, Seoane J, Fraga Rodriguez M, Gude Sampedro F, Romero J, Martin-Biedma B J Clin Med. 2022; 11(3).

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Relevance on the diagnosis of malignant lymphoma of the salivary gland.

Zhang X, Wang Z World J Clin Cases. 2020; 8(13):2717-2726.

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Intraoral plasmablastic lymphoma as a primary oral manifestation: A case report and review of literature.

Deshmukh R, Abhyankar P, Mhapuskar A, Varpe H J Oral Maxillofac Pathol. 2020; 24(Suppl 1):S91-S96.

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