Influence of Plant Growth Retardants on Quality of Codonopsis Radix

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2017 Oct 10

PMID 28991204

Citations 6

Authors

Yinyin Liao

Lanting Zeng

Pan Li

Tian Sun

Chao Wang

Fangwen Li

Yiyong Chen

Bing Du

Ziyin Yang

Affiliations

Soon will be listed here.

Abstract

Plant growth retardant (PGR) refers to organics that can inhibit the cell division of plant stem tip sub-apical meristem cells or primordial meristem cell. They are widely used in the cultivation of rhizomatous functional plants; such as that is a famous Chinese traditional herb. However, it is still unclear whether PGR affects the medicinal quality of . In the present study, amino acid analyses, targeted and non-targeted analyses by ultra-performance liquid chromatography combined with time-of-flight mass spectrometry (UPLC-TOF-MS) and gas chromatography-MS were used to analyze and compare the composition of untreated and treated with PGR. The contents of two key bioactive compounds, lobetyolin and atractylenolide III, were not affected by PGR treatment. The amounts of polysaccharides and some internal volatiles were significantly decreased by PGR treatment; while the free amino acids content was generally increased. Fifteen metabolites whose abundance were affected by PGR treatment were identified by UPLC-TOF-MS. Five of the up-regulated compounds have been reported to show immune activity, which might contribute to the healing efficacy ("buqi") of . The results of this study showed that treatment of with PGR during cultivation has economic benefits and affected some main bioactive compounds in .

Citing Articles

Regulatory Effects of Chlormequat Chloride on the Yield and Chemical Composition of Radix.

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Spraying humic acid regulator on cultivated (Franch.) Nannf. to improve yield of active constituents.

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Integrated Metabolome and Lipidome Strategy to Reveal the Action Pattern of Paclobutrazol, a Plant Growth Retardant, in Varying the Chemical Constituents of Platycodon Root.

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References

Foresti R, Hoque M, Monti D, Green C, Motterlini R . Differential activation of heme oxygenase-1 by chalcones and rosolic acid in endothelial cells. J Pharmacol Exp Ther. 2004; 312(2):686-93. DOI: 10.1124/jpet.104.074153. View

Weon J, Yun B, Lee J, Eom M, Ko H, Lee H . Neuroprotective Effect of Steamed and Fermented Codonopsis lanceolata. Biomol Ther (Seoul). 2014; 22(3):246-53. PMC: 4060076. DOI: 10.4062/biomolther.2014.019. View

He J, Ma N, Zhu S, Komatsu K, Li Z, Fu W . The genus Codonopsis (Campanulaceae): a review of phytochemistry, bioactivity and quality control. J Nat Med. 2014; 69(1):1-21. PMC: 4287686. DOI: 10.1007/s11418-014-0861-9. View

Jansen W, Hogenboom S, Thijssen M, Kamerling J, Vliegenthart J, Verhoef J . Synthetic 6B di-, tri-, and tetrasaccharide-protein conjugates contain pneumococcal type 6A and 6B common and 6B-specific epitopes that elicit protective antibodies in mice. Infect Immun. 2001; 69(2):787-93. PMC: 97953. DOI: 10.1128/IAI.69.2.787-793.2001. View

Hu H, Sun W, Xiao X, Tang X, Hu Q, Xu S . [Water extract from Codonopsis thalictrifolia wall affects the reproductive system of male infant rats]. Zhonghua Nan Ke Xue. 2014; 20(7):641-6. View

Thorpe S, Feizi T . Species differences in the expression of carbohydrate differentiation antigens on mammalian blood cells revealed by immunofluorescence with monoclonal antibodies. Biosci Rep. 1984; 4(8):673-85. DOI: 10.1007/BF01121021. View

Li X, Zhang X . [Influence of plant growth regulater on yield and quality of Salvia miltiorrhiza]. Zhongguo Zhong Yao Za Zhi. 2014; 39(11):1992-4. View

Rademacher W . GROWTH RETARDANTS: Effects on Gibberellin Biosynthesis and Other Metabolic Pathways. Annu Rev Plant Physiol Plant Mol Biol. 2004; 51:501-531. DOI: 10.1146/annurev.arplant.51.1.501. View

Wang K, Chen L, Wu C, Chang C, Wang C . Gastroprotective activity of atractylenolide III from Atractylodes ovata on ethanol-induced gastric ulcer in vitro and in vivo. J Pharm Pharmacol. 2010; 62(3):381-8. DOI: 10.1211/jpp.62.03.0014. View

10.

Yongxu S, Jicheng L . Structural characterization of a water-soluble polysaccharide from the roots of Codonopsis pilosula and its immunity activity. Int J Biol Macromol. 2008; 43(3):279-82. DOI: 10.1016/j.ijbiomac.2008.06.009. View

11.

Dumlu M, Gurkan E, Tuzlaci E . Chemical composition and antioxidant activity of Campanula alliariifolia. Nat Prod Res. 2008; 22(6):477-82. DOI: 10.1080/14786410701640429. View

12.

Fu X, Cheng S, Zhang Y, Du B, Feng C, Zhou Y . Differential responses of four biosynthetic pathways of aroma compounds in postharvest strawberry (Fragaria×ananassa Duch.) under interaction of light and temperature. Food Chem. 2016; 221:356-364. DOI: 10.1016/j.foodchem.2016.10.082. View

13.

Kang T, Bang J, Kim M, Kang I, Kim H, Jeong H . Atractylenolide III, a sesquiterpenoid, induces apoptosis in human lung carcinoma A549 cells via mitochondria-mediated death pathway. Food Chem Toxicol. 2010; 49(2):514-9. DOI: 10.1016/j.fct.2010.11.038. View

14.

Tengstrand E, Rosen J, Hellenas K, Aberg K . A concept study on non-targeted screening for chemical contaminants in food using liquid chromatography-mass spectrometry in combination with a metabolomics approach. Anal Bioanal Chem. 2012; 405(4):1237-43. PMC: 3548095. DOI: 10.1007/s00216-012-6506-5. View

15.

Kim E, Kim J, Jeon H, Kim S, Kim Y, Kim H . Chemical fingerprinting of Codonopsis pilosula and simultaneous analysis of its major components by HPLC-UV. Arch Pharm Res. 2014; 37(9):1148-58. DOI: 10.1007/s12272-014-0335-3. View

16.

Qin L, Yan Y, Wang Z . [Experimental study on the cardiotonic action of extract from Codonopsis pilosula (Franch.)Nannf]. Zhongguo Zhong Yao Za Zhi. 1994; 19(4):238-40, inside backcover. View

17.

Herrero M, Simo C, Garcia-Canas V, Ibanez E, Cifuentes A . Foodomics: MS-based strategies in modern food science and nutrition. Mass Spectrom Rev. 2011; 31(1):49-69. DOI: 10.1002/mas.20335. View

18.

Chen Y, Fu X, Mei X, Zhou Y, Cheng S, Zeng L . Proteolysis of chloroplast proteins is responsible for accumulation of free amino acids in dark-treated tea (Camellia sinensis) leaves. J Proteomics. 2017; 157:10-17. DOI: 10.1016/j.jprot.2017.01.017. View

19.

Mikkelsen M, Halkier B . Metabolic engineering of valine- and isoleucine-derived glucosinolates in Arabidopsis expressing CYP79D2 from Cassava. Plant Physiol. 2003; 131(2):773-9. PMC: 166853. DOI: 10.1104/pp.013425. View

20.

Li C, He L, Jin J . Atractylenolide I and atractylenolide III inhibit Lipopolysaccharide-induced TNF-alpha and NO production in macrophages. Phytother Res. 2007; 21(4):347-53. DOI: 10.1002/ptr.2040. View