» Articles » PMID: 28979174

Delayed Onset of Isolated Unilateral Oculomotor Nerve Palsy Caused by Post-Traumatic Pituitary Apoplexy: A Case Report

Overview
Publisher Sage Publications
Specialty General Medicine
Date 2017 Oct 6
PMID 28979174
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

Post-traumatic pituitary apoplexy is uncommon, most of which present with a sudden onset of severe headache and visual impairments associated with a dumbbell-shaped pituitary tumor. We experienced an unusual case of post-traumatic pituitary apoplexy with atypical clinical features. A 66-year-old man presented with mild cerebral contusion and an incidentally diagnosed intrasellar tumor after a fall accident with no loss of consciousness. The patients denied any symptoms before the accident. After 4 days, the left oculomotor nerve palsy developed and deteriorated associated with no severe headache. Repeated neuroimages suggested that pituitary apoplexy had occurred at admission and showed that the tumor compressed the left cavernous sinus. The patient underwent endonasal transsphenoidal surgery at 6 days after head injury, and the mass reduction improved the oculomotor nerve palsy completely within the following 14 days. The pathologic diagnosis was nonfunctioning pituitary adenoma with hemorrhage and necrosis.

Citing Articles

Pituitary Apoplexy in Patients with Pituitary Neuroendocrine Tumors (PitNET).

Gheorghe A, Trandafir A, Ionovici N, Carsote M, Nistor C, Popa F Biomedicines. 2023; 11(3).

PMID: 36979658 PMC: 10044830. DOI: 10.3390/biomedicines11030680.

References
1.
Bi W, Dunn I, Laws Jr E . Pituitary apoplexy. Endocrine. 2014; 48(1):69-75. DOI: 10.1007/s12020-014-0359-y. View

2.
Uchiyama H, Nishizawa S, Satoh A, Yokoyama T, Uemura K . Post-traumatic pituitary apoplexy--two case reports. Neurol Med Chir (Tokyo). 1999; 39(1):36-9. DOI: 10.2176/nmc.39.36. View

3.
Agrawal B, Dziurzynski K, Salamat M, Baskaya M . The temporal association of sphenoid sinus mucosal thickening on MR imaging with pituitary apoplexy. Turk Neurosurg. 2012; 22(6):785-90. DOI: 10.5137/1019-5149.JTN.4273-11.1. View

4.
Chuang C, Chen E, Huang Y, Tu P, Chen Y, Pai P . Surgical outcome of oculomotor nerve palsy in pituitary adenoma. J Clin Neurosci. 2011; 18(11):1463-8. DOI: 10.1016/j.jocn.2011.02.041. View

5.
Kashkouli M, Khalatbari M, Yahyavi S, Borghei-Razavi H, Soltan-Sanjari M . Pituitary apoplexy presenting as acute painful isolated unilateral third cranial nerve palsy. Arch Iran Med. 2008; 11(4):466-8. DOI: 08114/AIM.0022. View