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Acute Renal Failure Due to Organophosphate Poisoning: A Case Report

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Journal Cureus
Date 2017 Sep 30
PMID 28959515
Citations 8
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Abstract

Organophosphate (OP) poisoning is a commonly seen condition in many countries. OP poisoning classically presents with symptoms of cholinergic excess. It can rarely affect other organ systems but when it does, it can worsen a patient's overall prognosis. We present a case of a 23-year-old man with an extremely rare case of acute kidney injury due to OP, who was successfully treated with a combination of hemodialysis, atropine and pralidoxime days after OP poisoning with reservations on the aging process.

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References
1.
Patil G, Murthy N, Nikhil M . Contributing Factors for Morbidity and Mortality in Patients with Organophosphate Poisoning on Mechanical Ventilation: A Retrospective Study in a Teaching Hospital. J Clin Diagn Res. 2017; 10(12):UC18-UC20. PMC: 5296553. DOI: 10.7860/JCDR/2016/22116.9038. View

2.
Lee F, Chen W, Lin C, Lai C, Wu Y, Lin I . Organophosphate Poisoning and Subsequent Acute Kidney Injury Risk: A Nationwide Population-Based Cohort Study. Medicine (Baltimore). 2015; 94(47):e2107. PMC: 5058997. DOI: 10.1097/MD.0000000000002107. View

3.
Agostini M, Bianchin A . Acute renal failure from organophospate poisoning: a case of success with haemofiltration. Hum Exp Toxicol. 2003; 22(3):165-7. DOI: 10.1191/0960327103ht343cr. View

4.
Yurumez Y, Ikizceli I, Sozuer E, Soyuer I, Yucel Yavuz , Avsarogullari L . Effect of interleukin-10 on tissue damage caused by organophosphate poisoning. Basic Clin Pharmacol Toxicol. 2007; 100(5):323-7. DOI: 10.1111/j.1742-7843.2007.00049.x. View

5.
Khan N, Perez-Nunez R, Shamim N, Khan U, Naseer N, Feroze A . Intentional and unintentional poisoning in Pakistan: a pilot study using the Emergency Departments surveillance project. BMC Emerg Med. 2015; 15 Suppl 2:S2. PMC: 4682408. DOI: 10.1186/1471-227X-15-S2-S2. View