» Articles » PMID: 28951372

[Prior Periodontal Intervention Lowers Incidence of Lower Respiratory Infection in Patients Receiving Oral and Maxillofacial Tumor Surgery]

Overview
Specialty General Medicine
Date 2017 Sep 28
PMID 28951372
Authors
Affiliations
Soon will be listed here.
Abstract

Objective: To investigate whether periodontal infection is a risk factor for lower respiratory infection patients receiving oral and maxillofacial tumor surgery.

Methods: Patients undergoing oral and maxillofacial surgery for tumors with concurrent periodontal disease between January, 2012 and December, 2016 were randomized into periodontal intervention group and control group (treated with gargle solution containing chlorhexidine gluconate). The one-time periodontal intervention was completed within 24 h in the intervention group and two-week mouthwash was prescribed in the control group before oral and maxillofacial tumor surgery. Five periodontal indexes were examined at baseline and at 6 weeks after the treatment. The clinical symptoms and incidence of lower respiratory infections were compared between the two groups at 6 weeks.

Results: The PLI, BOP, PPD, and CAL were significantly lower and GR was higher in the intervention group than in the control group (P<0.01). The periodontal status was significantly improved in the intervention group. The incidence of lower respiratory infection was significantly lower in the intervention group than in the control group (2.22% vs 7.11%, P<0.01). The incidences of cough and expectoration in the intervention group were significantly lower than those in control group (P<0.01).

Conclusions: Periodontal infection is one of the risk factors for lower respiratory infection after oral and maxillofacial tumor surgery. The periodontal status can be effectively controlled and improved by periodontal intervention. Compared with mouthwash, periodontal intervention can significantly reduce the incidences of cough and expectoration and lower the incidence of lower respiratory infections.

References
1.
Gomes-Filho I, Santos C, Cruz S, Passos J, Cerqueira E, Costa M . Periodontitis and nosocomial lower respiratory tract infection: preliminary findings. J Clin Periodontol. 2009; 36(5):380-7. DOI: 10.1111/j.1600-051X.2009.01387.x. View

2.
Lee D, Kim S, Nam S, Choi S, Choi J, Roh J . Risk factors of surgical site infection in patients undergoing major oncological surgery for head and neck cancer. Oral Oncol. 2011; 47(6):528-31. DOI: 10.1016/j.oraloncology.2011.04.002. View

3.
Porto A, Cortelli S, Borges A, Matos F, Aquino D, Miranda T . Oral and endotracheal tubes colonization by periodontal bacteria: a case-control ICU study. Eur J Clin Microbiol Infect Dis. 2016; 35(3):343-51. DOI: 10.1007/s10096-015-2518-3. View

4.
Zhou X, Han J, Liu Z, Song Y, Wang Z, Sun Z . Effects of periodontal treatment on lung function and exacerbation frequency in patients with chronic obstructive pulmonary disease and chronic periodontitis: a 2-year pilot randomized controlled trial. J Clin Periodontol. 2014; 41(6):564-72. DOI: 10.1111/jcpe.12247. View

5.
Romero S, Horacio Pinto E, Longo P, Dal Corso S, Lanza F, Stelmach R . Effects of periodontal treatment on exacerbation frequency and lung function in patients with chronic periodontitis: study protocol of a 1-year randomized controlled trial. BMC Pulm Med. 2017; 17(1):23. PMC: 5259840. DOI: 10.1186/s12890-016-0340-z. View