Legionella Pneumophila-induced Cell Death: Two Hosts, Two Responses

Overview

Journal Virulence

Specialty Microbiology

Date 2017 Sep 27

PMID 28949864

Citations 2

Authors

Ascel Samba-Louaka

Affiliations

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References

Gao L, Harb O, Kwaik Y . Identification of macrophage-specific infectivity loci (mil) of Legionella pneumophila that are not required for infectivity of protozoa. Infect Immun. 1998; 66(3):883-92. PMC: 107991. DOI: 10.1128/IAI.66.3.883-892.1998. View

Saheb E, Trzyna W, Bush J . Caspase-like proteins: Acanthamoeba castellanii metacaspase and Dictyostelium discoideum paracaspase, what are their functions?. J Biosci. 2014; 39(5):909-16. DOI: 10.1007/s12038-014-9486-0. View

Truchan H, Christman H, White R, Rutledge N, Cianciotto N . Type II Secretion Substrates of Translocate Out of the Pathogen-Occupied Vacuole via a Semipermeable Membrane. mBio. 2017; 8(3). PMC: 5478897. DOI: 10.1128/mBio.00870-17. View

Silveira T, Zamboni D . Pore formation triggered by Legionella spp. is an Nlrc4 inflammasome-dependent host cell response that precedes pyroptosis. Infect Immun. 2010; 78(3):1403-13. PMC: 2825914. DOI: 10.1128/IAI.00905-09. View

Fontana M, Banga S, Barry K, Shen X, Tan Y, Luo Z . Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila. PLoS Pathog. 2011; 7(2):e1001289. PMC: 3040669. DOI: 10.1371/journal.ppat.1001289. View

Trzyna W, Legras X, Cordingley J . A type-1 metacaspase from Acanthamoeba castellanii. Microbiol Res. 2006; 163(4):414-23. DOI: 10.1016/j.micres.2006.06.017. View

Mou Q, Leung P . Differential expression of virulence genes in Legionella pneumophila growing in Acanthamoeba and human monocytes. Virulence. 2017; 9(1):185-196. PMC: 5955191. DOI: 10.1080/21505594.2017.1373925. View

Ohno A, Kato N, Sakamoto R, Kimura S, Yamaguchi K . Temperature-dependent parasitic relationship between Legionella pneumophila and a free-living amoeba (Acanthamoeba castellanii). Appl Environ Microbiol. 2008; 74(14):4585-8. PMC: 2493147. DOI: 10.1128/AEM.00083-08. View

Labbe K, Saleh M . Cell death in the host response to infection. Cell Death Differ. 2008; 15(9):1339-49. DOI: 10.1038/cdd.2008.91. View

10.

Hubber A, Roy C . Modulation of host cell function by Legionella pneumophila type IV effectors. Annu Rev Cell Dev Biol. 2010; 26:261-83. DOI: 10.1146/annurev-cellbio-100109-104034. View

11.

Ge J, Gong Y, Xu Y, Shao F . Preventing bacterial DNA release and absent in melanoma 2 inflammasome activation by a Legionella effector functioning in membrane trafficking. Proc Natl Acad Sci U S A. 2012; 109(16):6193-8. PMC: 3341053. DOI: 10.1073/pnas.1117490109. View

12.

Jorgensen I, Rayamajhi M, Miao E . Programmed cell death as a defence against infection. Nat Rev Immunol. 2017; 17(3):151-164. PMC: 5328506. DOI: 10.1038/nri.2016.147. View

13.

Zhu W, Hammad L, Hsu F, Mao Y, Luo Z . Induction of caspase 3 activation by multiple Legionella pneumophila Dot/Icm substrates. Cell Microbiol. 2013; 15(11):1783-95. PMC: 3797225. DOI: 10.1111/cmi.12157. View

14.

Banga S, Gao P, Shen X, Fiscus V, Zong W, Chen L . Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family. Proc Natl Acad Sci U S A. 2007; 104(12):5121-6. PMC: 1829273. DOI: 10.1073/pnas.0611030104. View

15.

Escoll P, Rolando M, Gomez-Valero L, Buchrieser C . From amoeba to macrophages: exploring the molecular mechanisms of Legionella pneumophila infection in both hosts. Curr Top Microbiol Immunol. 2013; 376:1-34. DOI: 10.1007/82_2013_351. View

16.

Wu D, Qiao K, Feng M, Fu Y, Cai J, Deng Y . Apoptosis of Acanthamoeba castellanii Trophozoites Induced by Oleic Acid. J Eukaryot Microbiol. 2017; 65(2):191-199. DOI: 10.1111/jeu.12454. View

17.

Mossine V, Waters J, Chance D, Mawhinney T . Transient Proteotoxicity of Bacterial Virulence Factor Pyocyanin in Renal Tubular Epithelial Cells Induces ER-Related Vacuolation and Can Be Efficiently Modulated by Iron Chelators. Toxicol Sci. 2017; 155(2):512. PMC: 6312079. DOI: 10.1093/toxsci/kfw214. View

18.

Barker J, Scaife H, Brown M . Intraphagocytic growth induces an antibiotic-resistant phenotype of Legionella pneumophila. Antimicrob Agents Chemother. 1995; 39(12):2684-8. PMC: 163012. DOI: 10.1128/AAC.39.12.2684. View

19.

Isberg R, OConnor T, Heidtman M . The Legionella pneumophila replication vacuole: making a cosy niche inside host cells. Nat Rev Microbiol. 2008; 7(1):13-24. PMC: 2631402. DOI: 10.1038/nrmicro1967. View

20.

Mengue L, Regnacq M, Aucher W, Portier E, Hechard Y, Samba-Louaka A . Legionella pneumophila prevents proliferation of its natural host Acanthamoeba castellanii. Sci Rep. 2016; 6:36448. PMC: 5091012. DOI: 10.1038/srep36448. View