Diols As Dienophiles: Bridged Carbocycles Via Ruthenium(0)-Catalyzed Transfer Hydrogenative Cycloadditions of Cyclohexadiene or Norbornadiene

Overview

Journal Angew Chem Int Ed Engl

Specialty Chemistry

Date 2017 Sep 24

PMID 28941001

Citations 8

Authors

Hiroki Sato

Keisuke Fukaya

Binit Sharma Poudel

Michael J Krische

Affiliations

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Abstract

Highly exo-selective ruthenium(0) catalyzed transfer hydrogenative cycloadditions of 1,2-diols with cyclohexadiene or norbornadiene are described. Novel bridged bicyclic ring systems are accessible from the diol, α-ketol or 1,2-dione oxidation levels with complete control of diastereoselectivity.

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