Green Cellulose-based Nanocomposite Catalyst: Design and Facile Performance in Aqueous Synthesis of Pyranopyrimidines and Pyrazolopyranopyrimidines

A cellulose-based nanobiocomposite decorated with FeO nanoparticles was prepared, characterized and applied as an easily recoverable and reusable green nanocatalyst in the synthesis of pyrano[2,3-d]pyrimidine derivatives in water at room temperature. The characterization was performed by using a variety of conventional analytical instruments such as Fourier transform infrared spectra (FT-IR), field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), energy dispersive X-ray (EDX), vibrating sample magnetometer (VSM), thermal analysis (TGA/DTA) and inductively coupled plasma atomic emission spectroscopy (ICP-AES) analyses. Two series of pyranopyrimidine and pyrazolopyranopyrimidines derivatives were synthesized by using the present cellulose-based nanocomposite. This protocol has valuable features like high yield of the products, short reaction times, mild conditions and easy work-up procedure. In addition, the catalyst can be prepared easily with cheap and green starting materials.