Biomedical Applications of Polyhydroxyalkanoates

Overview

Journal Indian J Microbiol

Specialty Microbiology

Date 2017 Sep 15

PMID 28904409

Citations 40

Authors

Subhasree Ray

Vipin Chandra Kalia

Affiliations

Soon will be listed here.

Abstract

Polyhydroxyalkanoates (PHA) are produced by a large number of microbes under stress conditions such as high carbon (C) availability and limitations of nutrients such as nitrogen, potassium, phosphorus, magnesium, and oxygen. Here, microbes store C as granules of PHAs-energy reservoir. PHAs have properties, which are quite similar to those of synthetic plastics. The unique properties, which make them desirable materials for biomedical applications is their biodegradability, biocompatibility, and non-toxicity. PHAs have been found suitable for various medical applications: biocontrol agents, drug carriers, biodegradable implants, tissue engineering, memory enhancers, and anticancer agents.

Citing Articles

Enhancing the Potential of PHAs in Tissue Engineering Applications: A Review of Chemical Modification Methods.

Chaber P, Andra-Zmuda S, Smigiel-Gac N, Zieba M, Dawid K, Martinka Maksymiak M Materials (Basel). 2024; 17(23).

PMID: 39685265 PMC: 11642177. DOI: 10.3390/ma17235829.

Materials designed to degrade: structure, properties, processing, and performance relationships in polyhydroxyalkanoate biopolymers.

Lalonde J, Pilania G, Marrone B Polym Chem. 2024; 16(3):235-265.

PMID: 39464417 PMC: 11498330. DOI: 10.1039/d4py00623b.

Targeted PHA Microsphere-Loaded Triple-Drug System with Sustained Drug Release for Synergistic Chemotherapy and Gene Therapy.

Wang S, Zhang C, Liu H, Fan X, Fu S, Li W Nanomaterials (Basel). 2024; 14(20).

PMID: 39452993 PMC: 11510473. DOI: 10.3390/nano14201657.

Green Synthesis of Bioplastics from Microalgae: A State-of-the-Art Review.

Adetunji A, Erasmus M Polymers (Basel). 2024; 16(10).

PMID: 38794516 PMC: 11124873. DOI: 10.3390/polym16101322.

Manipulating Microbial Cell Morphology for the Sustainable Production of Biopolymers.

Kalia V, Patel S, Karthikeyan K, Jeya M, Kim I, Lee J Polymers (Basel). 2024; 16(3).

PMID: 38337299 PMC: 10857275. DOI: 10.3390/polym16030410.

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