Identifying Gaps in Respiratory Syncytial Virus Disease Epidemiology in the United States Prior to the Introduction of Vaccines

Overview

Journal Clin Infect Dis

Publisher Oxford University Press

Specialty Infectious Diseases

Date 2017 Sep 15

PMID 28903503

Citations 28

Authors

Lindsay Kim

Brian Rha

Jon S Abramson

Larry J Anderson

Carrie L Byington

Grace L Chen

John DeVincenzo

Kathryn M Edwards

Janet A Englund

Ann R Falsey

Marie R Griffin

Ruth A Karron

Karen G Martin

H Cody Meissner

Flor M Munoz

Andrew T Pavia

Pedro A Piedra

William Schaffner

Eric A F Simoes

Rosalyn Singleton

H Keipp Talbot

Edward E Walsh

Jane R Zucker

Susan I Gerber

Affiliations

Soon will be listed here.

Abstract

Respiratory syncytial virus (RSV) causes lower respiratory tract illness frequently. No effective antivirals or vaccines for RSV are approved for use in the United States; however, there are at least 50 vaccines and monoclonal antibody products in development, with those targeting older adults and pregnant women (to protect young infants) in phase 2 and 3 clinical trials. Unanswered questions regarding RSV epidemiology need to be identified and addressed prior to RSV vaccine introduction to guide the measurement of impact and future recommendations. The Centers for Disease Control and Prevention (CDC) convened a technical consultation to gather input from external subject matter experts on their individual perspectives regarding evidence gaps in current RSV epidemiology in the United States, potential studies and surveillance platforms needed to fill these gaps, and prioritizing efforts. Participants articulated their individual views, and CDC staff synthesized individuals' input into this report.

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