5-year Long-term Efficacy of 120-W GreenLight Photoselective Vaporization of the Prostate for Benign Prostate Hyperplasia

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2017 Sep 14

PMID 28902866

Citations 2

Authors

Juhyun Park

Sung Yong Cho

Min Chul Cho

Hyeon Jeong

Hwancheol Son

Affiliations

Soon will be listed here.

Abstract

Purpose: To investigate 5-year long-term postoperative efficacy in benign prostate hyperplasia (BPH) following 120-W GreenLight high-performance system photoselective vaporization of the prostate (HPS-PVP).

Methods: This was a retrospective study of surgical outcomes in 159 men who underwent HPS-PVP and were followed over 60 months postoperatively. Definitions of treatment success were established based on the following three variables: international prostate symptom scores (IPSS), maximum flow rates (Qmax), and quality of life scores QoL). Logistic regression analyses were performed to determine predictors of the postoperative success.

Results: Postoperative IPSS/QoL, Qmax and post-voided residual urine volume were significantly improved after HPS-PVP. Postoperative Prostate specific antigen and prostate volume were also well reduced and sustained for 5 years. The postoperative success rate was assessed as 82.1%, 80.8% and 76.1% for each 1-, 3-, and 5-year. Thirty-eight (23.9%) patients had immediate postoperative complications, which were managed successfully with nonsurgical methods. None required transfusions, two (1.2%) patients required endoscopic reoperation for postoperative voiding difficulty due to bladder neck contracture or urethral stricture, and five (3.1%) required HPS-PVP reoperation. Presence of diabetes, voiding symptom subscore, QoL, maximal cystometric capacity, and bladder outlet obstructive index were valuable preoperative parameters for predicting postoperative success.

Conclusions: HPS-PVP is an effective, long-term treatment option for BPH, with sustained efficacy of 76.1% at 5-year follow up. Several preoperative parameters could help to predict the durable surgical improvements.

Citing Articles

Comparing GreenLight PVP and HoLEP beyond 5 years: A systematic review of long-term functional outcomes and reoperation rates.

Yim A, Alberto M, Yan X, Bolton D, Wong L, Sethi K BJUI Compass. 2025; 6(2):e483.

PMID: 39963584 PMC: 11832299. DOI: 10.1002/bco2.483.

Reoperation after surgical treatment for benign prostatic hyperplasia: a systematic review.

He W, Ding T, Niu Z, Hao C, Li C, Xu Z Front Endocrinol (Lausanne). 2023; 14:1287212.

PMID: 38027158 PMC: 10665564. DOI: 10.3389/fendo.2023.1287212.

Management of greenlight laser plus transurethral resection of prostate for elderly men.

Zhang Z, Luo F, Su Y, Li J Medicine (Baltimore). 2018; 97(33):e11862.

PMID: 30113481 PMC: 6112907. DOI: 10.1097/MD.0000000000011862.

References

Hueber P, Ben-Zvi T, Liberman D, Bhojani N, Gautam G, Deklaj T . Mid term outcomes of initial 250 case experience with GreenLight 120W-HPS photoselective vaporization prostatectomy for benign prostatic hyperplasia: comparison of prostate volumes < 60 cc, 60 cc-100 cc and > 100 cc. Can J Urol. 2012; 19(5):6450-8. View

Rieken M, Bachmann A . Laser treatment of benign prostate enlargement--which laser for which prostate?. Nat Rev Urol. 2014; 11(3):142-52. DOI: 10.1038/nrurol.2014.23. View

Toppercer A, Tetreault J . Compliance of the bladder: an attempt to establish normal values. Urology. 1979; 14(2):204-5. DOI: 10.1016/0090-4295(79)90164-x. View

Son H, Ro Y, Min S, Choo M, Kim J, Lee C . Modified vaporization-resection for photoselective vaporization of the prostate using a GreenLight high-performance system 120-W Laser: the Seoul technique. Urology. 2010; 77(2):427-32. DOI: 10.1016/j.urology.2010.06.034. View

Welch G, Weinger K, Barry M . Quality-of-life impact of lower urinary tract symptom severity: results from the Health Professionals Follow-up Study. Urology. 2002; 59(2):245-50. DOI: 10.1016/s0090-4295(01)01506-0. View

Homma Y, Kawabe K, Tsukamoto T, Yamaguchi O, Okada K, Aso Y . Estimate criteria for efficacy of treatment in benign prostatic hyperplasia. Int J Urol. 1996; 3(4):267-73. DOI: 10.1111/j.1442-2042.1996.tb00532.x. View

Son H, Song S, Paick J . Current laser treatments for benign prostatic hyperplasia. Korean J Urol. 2010; 51(11):737-44. PMC: 2991569. DOI: 10.4111/kju.2010.51.11.737. View

Ryoo H, Suh Y, Kim T, Sung H, Jeong J, Lee K . Efficacy of Holmium Laser Enucleation of the Prostate Based on Patient Preoperative Characteristics. Int Neurourol J. 2016; 19(4):278-85. PMC: 4703936. DOI: 10.5213/inj.2015.19.4.278. View

Kollmorgen T, Malek R, Barrett D . Laser prostatectomy: two and a half years' experience with aggressive multifocal therapy. Urology. 1996; 48(2):217-22. DOI: 10.1016/S0090-4295(96)00157-4. View

10.

Nitti V . Pressure flow urodynamic studies: the gold standard for diagnosing bladder outlet obstruction. Rev Urol. 2006; 7 Suppl 6:S14-21. PMC: 1477621. View

11.

Seki N, Nomura H, Yamaguchi A, Naito S . Evaluation of the learning curve for photoselective vaporization of the prostate over the course of 74 cases. J Endourol. 2008; 22(8):1731-5. DOI: 10.1089/end.2007.0368. View

12.

Rieken M, Ebinger Mundorff N, Bonkat G, Wyler S, Bachmann A . Complications of laser prostatectomy: a review of recent data. World J Urol. 2010; 28(1):53-62. DOI: 10.1007/s00345-009-0504-z. View

13.

Guo S, Muller G, Lehmann K, Talimi S, Bonkat G, Puschel H . The 80-W KTP GreenLight laser vaporization of the prostate versus transurethral resection of the prostate (TURP): adjusted analysis of 5-year results of a prospective non-randomized bi-center study. Lasers Med Sci. 2015; 30(3):1147-51. DOI: 10.1007/s10103-015-1721-x. View

14.

Unnikrishnan R, Almassi N, Fareed K . Benign prostatic hyperplasia: Evaluation and medical management in primary care. Cleve Clin J Med. 2017; 84(1):53-64. DOI: 10.3949/ccjm.84a.16008. View

15.

Rassweiler J, Teber D, Kuntz R, Hofmann R . Complications of transurethral resection of the prostate (TURP)--incidence, management, and prevention. Eur Urol. 2006; 50(5):969-79. DOI: 10.1016/j.eururo.2005.12.042. View

16.

Nair S, Pimentel M, Gilling P . A Review of Laser Treatment for Symptomatic BPH (Benign Prostatic Hyperplasia). Curr Urol Rep. 2016; 17(6):45. DOI: 10.1007/s11934-016-0603-5. View

17.

Pereira-Correia J, de Moraes Sousa K, Santos J, de Morais Perpetuo D, Lopes-da-Silva L, Krambeck R . GreenLight HPS™ 120-W laser vaporization vs transurethral resection of the prostate (<60 mL): a 2-year randomized double-blind prospective urodynamic investigation. BJU Int. 2012; 110(8):1184-9. DOI: 10.1111/j.1464-410X.2011.10878.x. View

18.

Cho S, Park S, Jeong M, Ro Y, Son H . 120W GreenLight High Performance System laser for benign prostate hyperplasia: 68 patients with 3-year follow-up and analysis of predictors of response. Urology. 2012; 80(2):396-401. DOI: 10.1016/j.urology.2012.01.063. View

19.

Hai M . Photoselective vaporization of prostate: five-year outcomes of entire clinic patient population. Urology. 2009; 73(4):807-10. DOI: 10.1016/j.urology.2008.08.502. View

20.

Malek R, Kuntzman R, Barrett D . Photoselective potassium-titanyl-phosphate laser vaporization of the benign obstructive prostate: observations on long-term outcomes. J Urol. 2005; 174(4 Pt 1):1344-8. DOI: 10.1097/01.ju.0000173913.41401.67. View