Metastatic Ewing's Sarcoma: Revisiting the "Evidence on the Fence"

Overview

Journal Indian J Med Paediatr Oncol

Publisher Thieme

Specialty Oncology

Date 2017 Sep 14

PMID 28900327

Citations 17

Authors

Nehal Khanna

Avinash Pandey

Jyoti Bajpai

Affiliations

Soon will be listed here.

Abstract

Metastatic Ewing's sarcoma is a challenging disease for oncology care providers with wide spectrum of disease at presentation, widely varying approach to the treatment and varied outcomes. The paucity of randomized evidence is a barrier in developing a consensus. This perspective provides the evidence "for and against" the benefit of aggressive approach including local and systemic therapy in patients presenting with metastatic Ewing's sarcoma and provide general recommendations so as to help select patients who will benefit with definitive intent treatment and also, avoid aggressive approach in patients with dismal outcome.

Citing Articles

Multiple primary malignancies: sequential development of Ewing sarcoma and carcinoid tumor in a single patient.

Ali H, Adhikari D, Noor A, Abbas H, Saqib H, Siddiqa A Ann Med Surg (Lond). 2024; 86(10):6322-6325.

PMID: 39359770 PMC: 11444556. DOI: 10.1097/MS9.0000000000002561.

Surgical Outcomes in Paediatric Lower Limb Sarcomas: A Single Institutional Experience.

Rajan S, Hindiskere S, Chinder P Indian J Surg Oncol. 2024; 15(Suppl 1):106-111.

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Incidence of skeletal-related events in patients with Ewing sarcoma: An observational retrospective study in Japan.

Aiba H, Kojima Y, Shimoi T, Sudo K, Yazaki S, Imai T Cancer Med. 2024; 13(5):e7060.

PMID: 38466026 PMC: 10926881. DOI: 10.1002/cam4.7060.

Extraskeletal Ewing's sarcoma of the mediastinum: Case report.

Caltavituro A, Buonaiuto R, Salomone F, Morra R, Pietroluongo E, De Placido P Front Oncol. 2023; 13:1074378.

PMID: 36776337 PMC: 9911166. DOI: 10.3389/fonc.2023.1074378.

Harnessing immunomodulation during DNA damage in Ewing sarcoma.

Daley J, Olson A, Bailey K Front Oncol. 2022; 12:1048705.

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