Dacryoadenitis with Ptosis and Diplopia As the Initial Presentation of Granulomatosis with Polyangiitis

Overview

Journal Intern Med

Specialty General Medicine

Date 2017 Sep 9

PMID 28883246

Citations 6

Authors

Makoto Hibino

Tetsuri Kondo

Affiliations

Soon will be listed here.

Abstract

A 77-year-old Japanese woman presented to an ophthalmologist with an erythematous swollen upper eyelid and diplopia which was initially diagnosed to be idiopathic dacryoadenitis on the basis of a histological evaluation of an orbital mass that was in remission following a 3.5-month period of systemic corticosteroid therapy. She subsequently developed respiratory symptoms, and was finally diagnosed with systemic granulomatosis with polyangiitis (GPA) based on the clinical and histological features. She was successfully treated with corticosteroids and azathioprine. Dacryoadenitis in the form of an orbital inflammatory pseudotumor may be an initial presenting feature of GPA, sometimes as the limited phenotype, and occasionally progressing to systemic disease.

Citing Articles

Dacryoadenitis: do not forget ANCA vasculitis.

Derbel A, Ben Salah R, Boukhzar R, Frikha F, Marzouk S, Bahloul Z Rom J Ophthalmol. 2024; 68(2):187-190.

PMID: 39006332 PMC: 11238856. DOI: 10.22336/rjo.2024.35.

Granulomatosis with Polyangiitis (GPA)-A Multidisciplinary Approach of a Case Report.

Trandafir C, Balica N, Horhat D, Mot I, Sarau C, Poenaru M Medicina (Kaunas). 2022; 58(12).

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Clinical Characteristics of Idiopathic Orbital Inflammation Syndrome in Relation to Intraocular Pressure.

Otsuka M, Yunoki T, Ozaki H, Hayashi A Clin Ophthalmol. 2022; 16:1467-1473.

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Atypical Granulomatosis with Polyangiitis Presenting with Meibomitis, Scleritis, Uveitis and Papillary Bladder Tumor: A Case Report and Literature Review.

Kojima T, Dogru M, Shimizu E, Yazu H, Takahashi A, Shimazaki J Diagnostics (Basel). 2021; 11(4).

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Orbital Vasculitides-Differential Diagnosis.

Espinoza G, Liu J Curr Rheumatol Rep. 2019; 21(10):54.

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