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Therapies for Advanced Stage Hepatocellular Carcinoma with Macrovascular Invasion or Metastatic Disease: A Systematic Review and Meta-analysis

Overview
Journal Hepatology
Specialty Gastroenterology
Date 2017 Sep 8
PMID 28881497
Citations 122
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Abstract

Conclusion: In patients with advanced HCC and CP A liver function, sorafenib is the only treatment that has been shown to improve OS in randomized studies. High-quality data supporting the use of other treatment modalities in this setting, or in the setting of patients with less compensated (CP B) liver disease, are lacking. (Hepatology 2018;67:422-435).

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