General Anaesthesia for Patients with a History of a Contrast Medium-induced Anaphylaxis: a Useful Prophylaxis?
Overview
Authors
Affiliations
Contrast-enhanced radiological examinations are important diagnostic tools in modern medicine. Currently, all approved and available iodinated and gadolinium-based contrast agents are safe and well-tolerated by most patients. However, approximately 2% of patients receiving iodinated contrast media exhibit hypersensitivity reactions. Patients with a history of such a reaction are at increased risk upon reexposure. Therefore, they are subjected to a prophylaxis such as injection of antiallergy drugs or general anaesthesia. The latter procedure is expensive, can burden the patients organism, and besides lacks objective verification. Therefore, the purpose of our review paper is to present and discuss the background and the previous practice, as well as to provide a proposal for a safe individual patient management.
Kou E, Zhang X, Dong B, Wang B, Zhu Y Life (Basel). 2024; 14(2).
PMID: 38398673 PMC: 10890042. DOI: 10.3390/life14020164.
Xu W, Liu Y Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2023; 48(8):1225-1233.
PMID: 37875363 PMC: 10930856. DOI: 10.11817/j.issn.1672-7347.2023.220537.
A humanized mouse model to study mast cells mediated cutaneous adverse drug reactions.
Mencarelli A, Gunawan M, Yong K, Bist P, Tan W, Tan S J Leukoc Biol. 2020; 107(5):797-807.
PMID: 31922289 PMC: 7322799. DOI: 10.1002/JLB.3MA1219-210RR.