Forsythiae Fructus: A Review on Its Phytochemistry, Quality Control, Pharmacology and Pharmacokinetics

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2017 Sep 5

PMID 28869577

Citations 33

Authors

Zhanglu Dong

Xianyuan Lu

Xueli Tong

Yaqian Dong

Lan Tang

Menghua Liu

Affiliations

Soon will be listed here.

Abstract

, as a traditional Chinese medicine, has been widely used both as a single herb and in compound prescriptions in Asia, mainly due to its heat-clearing and detoxifying effects. Modern pharmacology has proved possesses various therapeutic effects, both in vitro and in vivo, such as anti-inflammatory, antibacterial and antiviral activities. Up to now, three hundred and twenty-one compounds have been identified and sensitive analytical methods have been established for its quality control. Recently, the pharmacokinetics of and its bioactive compounds have been reported, providing valuable information for its clinical application. Therefore, this systematic review focused on the newest scientific reports on and extensively summarizes its phytochemistry, pharmacology, pharmacokinetics and standardization procedures, especially the difference between the two applied types-unripe and ripe -in the hope of providing a helpful reference and guide for its clinical applications and further studies.

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