Transmission of Human T Cell Lymphotropic Virus Type I by Blood Transfusion Before and After Mass Screening of Sera from Seropositive Donors

Overview

Journal Vox Sang

Specialty Hematology

Date 1987 Jan 1

PMID 2885977

Citations 18

Authors

S Kamihira

S NAKASIMA

Y Oyakawa

Y Moriuti

M Ichimaru

H Okuda

M Kanamura

T Oota

Affiliations

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Abstract

The human T cell lymphotropic virus type I (HTLV-I) is transmitted by blood transfusions that contain cell components as one of the virus transmission modes. We carried out mass screening of sera from seropositive donors by a gelatin particle agglutination test to prevent the spread of HTLV-I by transfusion. Seroconversion rates were compared before and after screening. The results show a remarkable decrease in the rate of infection from 53.6 to 0.9%. Therefore, it is certain that screening by the agglutination method prevents the spread of HTLV-I transmission in blood transfusions.

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