Prevalence and Associated Factors of Diabetic Retinopathy in Beijing, China: a Cross-sectional Study

Overview

Journal BMJ Open

Specialty General Medicine

Date 2017 Sep 1

PMID 28855199

Citations 33

Authors

Jing Cui

Ji-Ping Ren

Dong-Ning Chen

Zhong Xin

Ming-Xia Yuan

Jie Xu

Qi-Sheng You

Jin-Kui Yang

Affiliations

Soon will be listed here.

Abstract

Objectives: The study aimed to determine the exact risk factors for diabetic retinopathy (DR) in the Chinese population using a cohort of 17 985 individuals from Beijing, China.

Design: Cross-sectional study.

Setting: A hospital.

Participants: 17 985 individuals from Beijing, China.

Primary And Secondary Outcome Measures: This was a cross-sectional study of permanent residents from the Changping area (Beijing, China) recruited from July 2010 to March 2011 and from March 2014 to February 2015 during a routine health examination at the Tongren Hospital of Beijing. Eye examinations were conducted by experienced ophthalmologists. Medical history, height, weight, body mass index (BMI) and blood pressure were recorded. Routine laboratory examinations were performed.

Results: The prevalence of DR was 1.5% in the general study population and 8.1% among individuals with diabetes. Compared with the non-DR group, individuals in the DR group in the diabetes population had longer disease duration, higher systolic blood pressure (SBP), fasting plasma glucose (FPG) and uric acid (UA) (in men) and lower UA (in women) (all p<0.05). The multivariate analysis showed that disease duration (p<0.001), BMI (p=0.046), SBP (p=0.012), creatinine clearance rate (CCR) (p=0.014), UA (p=0.018) and FPG (p<0.001) were independently associated with DR in patients with diabetes.

Conclusion: The prevalence of DR was 8.1% among patients with diabetes. Disease duration, BMI, SBP, CCR, UA and FPG were independently associated with DR.

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