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Frailty May Be a Risk Marker for Adverse Outcome in Patients with Congestive Heart Failure

Overview
Journal ESC Heart Fail
Date 2017 Aug 24
PMID 28834671
Citations 24
Authors
Sumio Yamada
Kuniyasu Kamiya
Yuji Kono
Affiliations
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Abstract

Aims: To examine the availability of frailty concept with objective criteria for risk stratification in patients with congestive heart failure (CHF).

Methods And Results: Study design was secondary analysis of our CHF cohort. We selected 181 patients who completed clinical assessments and were successfully followed 2-year post discharge. To set frailty criteria, grip strength <26 kg in men and <17 kg in women (weakness) and performance measure for activities of daily living-8 ≧21 points (exhaustion) were defined for predicting 6 min walking distance <300 m (slowness) by the receiver-operating characteristics. During 2 years of follow up, subjects who met all the criteria had a 4 times greater risk of cardiac event compared with those with no frailty criteria.

Conclusion: The findings of present study suggest that frailty criteria may serve as a new clinical marker for management of patients with CHF.

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