Chemical Composition and Evaluation of the Antibacterial and Cytotoxic Activities of the Essential Oil from the Leaves of Myracrodruon Urundeuva

Overview

Journal BMC Complement Altern Med

Publisher Biomed Central

Specialty Rehabilitation Medicine

Date 2017 Aug 24

PMID 28830478

Citations 6

Authors

Italo Diego Reboucas de Araujo

Nayara Coriolano de Aquino

Andreza Conceicao Veras de Aguiar Guerra

Renato Ferreira de Almeida Junior

Renata Mendonca Araujo

Raimundo Fernandes de Araujo Junior

Kleber Juvenal Silva Farias

Jose Verissimo Fernandes

Vania Sousa Andrade

Affiliations

Soon will be listed here.

Abstract

Background: This study evaluated the in vitro activity of essential oil extracted from the leaves of Myracrodruon urundeuva.

Methods: The oil was obtained by hydro-distillation and characterized by Gas Chromatography coupled to Mass Spectrometry (GC-MS) and Gas Chromatography with Flame Ionization Detector (GC-FID). The antibacterial activity was evaluated by the broth microdilution technique and the MIF was determined by using growth indicator CTT (2,3,5-triphenyl-tetrazolium) and CBM in BHI agar. The oil's cytotoxicity was evaluated in HeLa, HEK-293, and Vero E6 cells using MTT, 3- (4,5-dimethylthiazol-2-yl) -2,5-diphenyl tetrazolium.

Results: The oil showed chemical markers, including α-pinene (87.85%), trans-caryophyllene (1.57%), limonene (1.49%) and β -pinene (1.42%), and activity against all strains: Staphylococcus aureus (MIC = MBC = 0.22 mg/mL), Staphylococcus epidermidis (MIC = 0.11 mg/mL and MBC = 0.22 mg/mL), Escherichia coli (MIC = 0.88 mg/mL and MBC = 1.75 mg/mL), Pseudomonas aeruginosa (MIC = MBC = 7 mg/mL) and Salmonella Enteritidis (MIC = MBC = 0.44 mg/mL). In vitro cytotoxicity tests showed that the oil is not toxic and has slight antitumor activity.

Conclusions: We conclude that the M. urundeuva oil results are promising, with prospects of being pharmacologically viable.

Citing Articles

Pimarane Diterpenoids from Aerial Parts of and Their Antimicrobial Activity.

Pandey J, Hwang B, Lee H, Poudel A Evid Based Complement Alternat Med. 2022; 2022:5178880.

PMID: 35154345 PMC: 8837446. DOI: 10.1155/2022/5178880.

Composition and pharmacological activity of essential oils from two imported fruit samples.

Alam A, Singh V J Taibah Univ Med Sci. 2021; 16(2):231-239.

PMID: 33897328 PMC: 8046960. DOI: 10.1016/j.jtumed.2020.10.007.

Antioxidant, Anti-Biofilm, and Solar Protection Activities of (Britton & Rose) Pulp Extract.

Queiroz Aquino-Martins V, de Melo L, Silva L, Targino de Lima T, Queiroz M, Viana R Antioxidants (Basel). 2019; 8(10).

PMID: 31581486 PMC: 6826963. DOI: 10.3390/antiox8100439.

Phytochemical analysis and evaluation of the cytotoxic, antimicrobial and antioxidant activities of essential oils from three Plectranthus species grown in Saudi Arabia.

Mothana R, Khaled J, Noman O, Kumar A, Alajmi M, Al-Rehaily A BMC Complement Altern Med. 2018; 18(1):237.

PMID: 30097042 PMC: 6086039. DOI: 10.1186/s12906-018-2302-x.

Myracrodruon urundeuva seed exudates proteome and anthelmintic activity against Haemonchus contortus.

Soares A, Oliveira J, Rocha C, Ferreira A, Perales J, Zanatta A PLoS One. 2018; 13(7):e0200848.

PMID: 30024949 PMC: 6053183. DOI: 10.1371/journal.pone.0200848.

References

Lee J, Yang H, Lee H, Hong S . Chemical composition and antimicrobial activity of essential oil from cones of Pinus koraiensis. J Microbiol Biotechnol. 2008; 18(3):497-502. View

Costerton J, Ingram J, Cheng K . Structure and function of the cell envelope of gram-negative bacteria. Bacteriol Rev. 1974; 38(1):87-110. PMC: 413842. DOI: 10.1128/br.38.1.87-110.1974. View

Jalan R, Fernandez J, Wiest R, Schnabl B, Moreau R, Angeli P . Bacterial infections in cirrhosis: a position statement based on the EASL Special Conference 2013. J Hepatol. 2014; 60(6):1310-24. DOI: 10.1016/j.jhep.2014.01.024. View

Petrelli R, Orsomando G, Sorci L, Maggi F, Ranjbarian F, Biapa Nya P . Biological Activities of the Essential Oil from Erigeron floribundus. Molecules. 2016; 21(8). PMC: 6274054. DOI: 10.3390/molecules21081065. View

Alves T, Silva A, Brandao M, Grandi T, Smania E, Smania Junior A . Biological screening of Brazilian medicinal plants. Mem Inst Oswaldo Cruz. 2000; 95(3):367-73. DOI: 10.1590/s0074-02762000000300012. View

Nissen L, Zatta A, Stefanini I, Grandi S, Sgorbati B, Biavati B . Characterization and antimicrobial activity of essential oils of industrial hemp varieties (Cannabis sativa L.). Fitoterapia. 2009; 81(5):413-9. DOI: 10.1016/j.fitote.2009.11.010. View

DCosta V, King C, Kalan L, Morar M, Sung W, Schwarz C . Antibiotic resistance is ancient. Nature. 2011; 477(7365):457-61. DOI: 10.1038/nature10388. View

Crivelaro de Menezes T, Delbem A, Brighenti F, Okamoto A, Gaetti-Jardim Jr E . Protective efficacy of Psidium cattleianum and Myracrodruon urundeuva aqueous extracts against caries development in rats. Pharm Biol. 2010; 48(3):300-5. DOI: 10.3109/13880200903122202. View

Chiang P, Burrows L . Biofilm formation by hyperpiliated mutants of Pseudomonas aeruginosa. J Bacteriol. 2003; 185(7):2374-8. PMC: 151504. DOI: 10.1128/JB.185.7.2374-2378.2003. View

10.

Rattanachaikunsopon P, Phumkhachorn P . Antimicrobial activity of basil (Ocimum basilicum) oil against Salmonella enteritidis in vitro and in food. Biosci Biotechnol Biochem. 2010; 74(6):1200-4. DOI: 10.1271/bbb.90939. View

11.

Unlu M, Ergene E, Vardar Unlu G, Zeytinoglu H, Vural N . Composition, antimicrobial activity and in vitro cytotoxicity of essential oil from Cinnamomum zeylanicum Blume (Lauraceae). Food Chem Toxicol. 2010; 48(11):3274-80. DOI: 10.1016/j.fct.2010.09.001. View

12.

Sylvestre M, Pichette A, Longtin A, Nagau F, Legault J . Essential oil analysis and anticancer activity of leaf essential oil of Croton flavens L. from Guadeloupe. J Ethnopharmacol. 2005; 103(1):99-102. DOI: 10.1016/j.jep.2005.07.011. View

13.

Edris A . Pharmaceutical and therapeutic potentials of essential oils and their individual volatile constituents: a review. Phytother Res. 2007; 21(4):308-23. DOI: 10.1002/ptr.2072. View

14.

Ben Hsouna A, Trigui M, Ben Mansour R, Jarraya R, Damak M, Jaoua S . Chemical composition, cytotoxicity effect and antimicrobial activity of Ceratonia siliqua essential oil with preservative effects against Listeria inoculated in minced beef meat. Int J Food Microbiol. 2011; 148(1):66-72. DOI: 10.1016/j.ijfoodmicro.2011.04.028. View

15.

Rashid S, Rather M, Shah W, Bhat B . Chemical composition, antimicrobial, cytotoxic and antioxidant activities of the essential oil of Artemisia indica Willd. Food Chem. 2012; 138(1):693-700. DOI: 10.1016/j.foodchem.2012.10.102. View

16.

Duarte A, Alencar de Menezes I, Braga M, Leite N, Barros L, Waczuk E . Antimicrobial Activity and Modulatory Effect of Essential Oil from the Leaf of Rhaphiodon echinus (Nees & Mart) Schauer on Some Antimicrobial Drugs. Molecules. 2016; 21(6). PMC: 6274211. DOI: 10.3390/molecules21060743. View

17.

Tacconelli E, Cataldo M, Dancer S, de Angelis G, Falcone M, Frank U . ESCMID guidelines for the management of the infection control measures to reduce transmission of multidrug-resistant Gram-negative bacteria in hospitalized patients. Clin Microbiol Infect. 2013; 20 Suppl 1:1-55. DOI: 10.1111/1469-0691.12427. View

18.

Montanari R, Barbosa L, Demuner A, Silva C, Andrade N, Ismail F . Exposure to Anacardiaceae volatile oils and their constituents induces lipid peroxidation within food-borne bacteria cells. Molecules. 2012; 17(8):9728-40. PMC: 6268019. DOI: 10.3390/molecules17089728. View

19.

Wang W, Li N, Luo M, Zu Y, Efferth T . Antibacterial activity and anticancer activity of Rosmarinus officinalis L. essential oil compared to that of its main components. Molecules. 2012; 17(3):2704-13. PMC: 6268287. DOI: 10.3390/molecules17032704. View

20.

Yu J, Lei J, Zhang X, Yu H, Tian D, Liao Z . Anticancer, antioxidant and antimicrobial activities of the essential oil of Lycopus lucidus Turcz. var. hirtus Regel. Food Chem. 2014; 126(4):1593-8. DOI: 10.1016/j.foodchem.2010.12.027. View