Right Heart Function During Acute Respiratory Distress Syndrome

Overview

Journal Ann Transl Med

Publisher AME Publishing Company

Date 2017 Aug 23

PMID 28828370

Citations 22

Authors

Xavier Repesse

Antoine Vieillard-Baron

Affiliations

Soon will be listed here.

Abstract

Acute respiratory distress syndrome (ARDS) is burdened with significant mortality, mainly in connection with circulatory failure. The right ventricle (RV) is the weak link of hemodynamic stability among ARDS patients and its failure, also named "severe" acute cor pulmonale (ACP), is responsible for excess mortality. Driving pressure ≥18 cmHO, PaCO ≥48 mmHg and PaO/FiO <150 mmHg are three preventable factors recently identified as independently associated with ACP, on which ventilator strategy designed to protect the RV has to focus. This is largely achieved by the use of early and extended sessions of prone positioning (PP) and by daily monitoring of the RV by echocardiography.

Citing Articles

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The impact of positive end-expiratory pressure on right ventricular function in patients with moderate-to-severe ARDS: a prospective paired-design study.

Xingzheng L, Weiguang G, Quanqiu Y, Huifen Z, Zijun Z, Qiming Z Front Med (Lausanne). 2024; 11:1424090.

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