Tuberculosis-Related Diabetes: Is It Reversible After Complete Treatment?

Overview

Journal Am J Trop Med Hyg

Specialty Tropical Medicine

Date 2017 Aug 19

PMID 28820679

Citations 11

Authors

Huma Aftab

Dirk L Christensen

Atiqa Ambreen

Mohammad Jamil

Peter Garred

Jorgen H Petersen

Susanne D Nielsen

Ib C Bygbjerg

Affiliations

Soon will be listed here.

Abstract

Individuals with newly diagnosed tuberculosis (TB) were screened for diabetes (DM) with fasting plasma glucose (FPG) in Pakistan. A significant decrease in FPG was observed when TB was treated. Of those with newly diagnosed DM, 46% and 62% no longer had hyperglycemia after 3 and 6 months, respectively. Individuals with known DM also showed a significant decrease in fasting plasma levels when treated for TB, but after 3 months none had normoglycemia, and after 6 months 9.2% were normoglycemic. Thus, TB-related DM may abate when the stress terminates, as is the case in gestational DM. However, because stress hyperglycemia may be associated with subsequent risk of developing DM, follow-up is recommended.

Citing Articles

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Association between prior tuberculosis disease and dysglycemia within an HIV-endemic, rural South African population.

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