The Evolution of Paroxysmal Nocturnal Haemoglobinuria Depends on Intensity of Immunosuppressive Therapy

Overview

Journal Br J Haematol

Specialty Hematology

Date 2017 Aug 15

PMID 28804905

Citations 9

Authors

Taha Bat

Omnia N Abdelhamid

Suresh K Balasubramanian

Aly Mai

Tomas Radivoyevitch

Michael Clemente

Jaroslaw P Maciejewski

Affiliations

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Citing Articles

Current status and perspectives of hematopoietic cell transplantation in patients with paroxysmal nocturnal hemoglobinuria.

Ussowicz M, Przystupski D, Mensah-Glanowska P, Piekarska A Front Immunol. 2025; 15():1521484.

PMID: 39840046 PMC: 11747312. DOI: 10.3389/fimmu.2024.1521484.

Current landscape of paroxysmal nocturnal hemoglobinuria in the era of complement inhibitors and regulators.

Shi J, Ozcan Y, Santos C, Patel H, Shammo J, Bat T Ther Adv Hematol. 2024; 15:20406207241307500.

PMID: 39734592 PMC: 11672493. DOI: 10.1177/20406207241307500.

Pathogenesis and inflammaging in myelodysplastic syndrome.

Villaume M, Savona M Haematologica. 2024; 110(2):283-299.

PMID: 39445405 PMC: 11788632. DOI: 10.3324/haematol.2023.284944.

Navigating the Complement Pathway to Optimize PNH Treatment with Pegcetacoplan and Other Currently Approved Complement Inhibitors.

Hillmen P, Horneff R, Yeh M, Kolev M, Deschatelets P Int J Mol Sci. 2024; 25(17).

PMID: 39273426 PMC: 11395449. DOI: 10.3390/ijms25179477.

Diagnostic evaluation in bone marrow failure disorders: what have we learnt to help inform the transplant decision in 2024 and beyond?.

Ciangola G, Santinelli E, McLornan D, Pagliuca S, Gurnari C Bone Marrow Transplant. 2024; 59(4):444-450.

PMID: 38291125 DOI: 10.1038/s41409-024-02213-6.

References

Young N, Maciejewski J . Genetic and environmental effects in paroxysmal nocturnal hemoglobinuria: this little PIG-A goes "Why? Why? Why?". J Clin Invest. 2000; 106(5):637-41. PMC: 381297. DOI: 10.1172/JCI11002. View

Maciejewski J, Follmann D, Nakamura R, Saunthararajah Y, Rivera C, Simonis T . Increased frequency of HLA-DR2 in patients with paroxysmal nocturnal hemoglobinuria and the PNH/aplastic anemia syndrome. Blood. 2001; 98(13):3513-9. DOI: 10.1182/blood.v98.13.3513. View

Maciejewski J, Rivera C, Kook H, Dunn D, Young N . Relationship between bone marrow failure syndromes and the presence of glycophosphatidyl inositol-anchored protein-deficient clones. Br J Haematol. 2002; 115(4):1015-22. DOI: 10.1046/j.1365-2141.2001.03191.x. View