Prognostic Stratification of Patients With Advanced Oral Cavity Squamous Cell Carcinoma

Overview

Journal Curr Oncol Rep

Publisher Current Science

Specialty Oncology

Date 2017 Aug 12

PMID 28799122

Citations 18

Authors

Dante De Paz

Huang-Kai Kao

Yenlin Huang

Kai-Ping Chang

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: Prognosis of advanced oral squamous cell carcinoma remains a challenge for clinicians despite progress in its diagnosis and treatment over the past decades. In this review, we assessed clinicopathological factors and potential biomarkers along with their prognostic relevance in an attempt to develop optimal treatment strategies for these patients.

Recent Findings: In addition to several pathologic factors that have been proposed to improve prognostic stratification and treatment planning in the eighth edition of the American Joint Committee staging manual on cancer, we reviewed some other imaging and clinicopathological parameters demonstrated to be closely associated with patient prognosis, along with the biomarkers related to novel target or immune therapy. Evaluation of current literature regarding the prognostic stratification used in contemporary clinicopathological studies and progress in the development of targeted or immune therapy may help these patients benefit from tailored and personalized treatment and obtain better oncological results.

Citing Articles

Evaluation of the Expression Levels of miR-21-5p and miR-429 Genes in Biopsy Samples from Patients with Oral Squamous Cell Carcinoma.

Garajei A, Allameh A, Azadi M, Emami A, Atashbasteh M, Mostafavi M Diagnostics (Basel). 2023; 13(7).

PMID: 37046462 PMC: 10093007. DOI: 10.3390/diagnostics13071244.

Demographic and pathologic factor regression to a growth rate model of p16-negative oral cavity squamous cell carcinoma.

Wihlidal J, Tay K, Macneil S, Nichols A, Fung K, Yoo J Laryngoscope Investig Otolaryngol. 2022; 7(5):1384-1390.

PMID: 36258883 PMC: 9575115. DOI: 10.1002/lio2.831.

A prognostic Risk Score model for oral squamous cell carcinoma constructed by 6 glycolysis-immune-related genes.

Liu Y, Wang T, Li R BMC Oral Health. 2022; 22(1):324.

PMID: 35922788 PMC: 9351085. DOI: 10.1186/s12903-022-02358-0.

Cell-Free RNA as a Novel Biomarker for Response to Therapy in Head & Neck Cancer.

Tosevska A, Morselli M, Basak S, Avila L, Mehta P, Wang M Front Oncol. 2022; 12:869108.

PMID: 35600369 PMC: 9121879. DOI: 10.3389/fonc.2022.869108.

BST2 promotes growth and induces gefitinib resistance in oral squamous cell carcinoma via regulating the EGFR pathway.

Jin H, Zhang L, Wang S, Qian L Arch Med Sci. 2021; 17(6):1772-1782.

PMID: 34900059 PMC: 8641506. DOI: 10.5114/aoms.2019.86183.

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