Satellite Transcripts Locally Promote Centromere Formation

Overview

Journal Dev Cell

Publisher Cell Press

Specialties Cell Biology
Reproductive Medicine

Date 2017 Aug 9

PMID 28787584

Citations 6

Authors

Carlos Perea-Resa

Michael D Blower

Affiliations

Soon will be listed here.

Abstract

Centromeric transcription is a common eukaryotic centromere feature, yet it is unclear how transcription is linked to underlying repetitive satellite sequences. In this issue of Developmental Cell, McNulty et al. (2017) show for human centromeres that all α-satellite sequences are transcribed into chromatin-bound RNAs and are required for centromere assembly.

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