Two Novel Poxviruses with Unusual Genome Rearrangements: NY_014 and Murmansk

Overview

Journal Virus Genes

Specialties Microbiology
Molecular Biology

Date 2017 Aug 2

PMID 28762208

Citations 12

Authors

Chad Smithson

Hermann Meyer

Crystal M Gigante

Jinxin Gao

Hui Zhao

Dhwani Batra

Inger Damon

Chris Upton

Yu Li

Affiliations

Soon will be listed here.

Abstract

The genome sequence and annotation of two novel poxviruses, NY_014 and Murmansk, are presented. Despite being isolated on different continents and from different hosts, the viruses are relatively similar, albeit distinct species. The closest known relative of the novel viruses is Yoka poxvirus. Five novel genes were found in these genomes, two of which were MHC class I homologs. Although the core of these genomes was well conserved, the terminal regions showed significant variability with large deletions and surprising evidence of recombination with orthopoxviruses.

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