Characterization, Preparation, and Purification of Marine Bioactive Peptides

Overview

Journal Biomed Res Int

Publisher Wiley

Specialties Biomedical Engineering
Biotechnology
General Medicine

Date 2017 Aug 2

PMID 28761878

Citations 29

Authors

Xueqin Wang

Huahua Yu

Ronge Xing

Pengcheng Li

Affiliations

Soon will be listed here.

Abstract

Marine bioactive peptides, as a source of unique bioactive compounds, are the focus of current research. They exert various biological roles, some of the most crucial of which are antioxidant activity, antimicrobial activity, anticancer activity, antihypertensive activity, anti-inflammatory activity, and so forth, and specific characteristics of the bioactivities are described. This review also describes various manufacturing techniques for marine bioactive peptides using organic synthesis, microwave assisted extraction, chemical hydrolysis, and enzymes hydrolysis. Finally, purification of marine bioactive peptides is described, including gel or size exclusion chromatography, ion-exchange column chromatography, and reversed-phase high-performance liquid chromatography, which are aimed at finding a fast, simple, and effective method to obtain the target peptides.

Citing Articles

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From Sea to Lab: Angiotensin I-Converting Enzyme Inhibition by Marine Peptides-Mechanisms and Applications.

Jo D, Khan F, Park S, Ko S, Kim K, Yang D Mar Drugs. 2024; 22(10).

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Bioactive Peptides from Marine Organisms.

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References

Wang X, Yu H, Xing R, Chen X, Liu S, Li P . Optimization of the Extraction and Stability of Antioxidative Peptides from Mackerel () Protein. Biomed Res Int. 2017; 2017:6837285. PMC: 5282459. DOI: 10.1155/2017/6837285. View

Duarte J, Vinderola G, Ritz B, Perdigon G, Matar C . Immunomodulating capacity of commercial fish protein hydrolysate for diet supplementation. Immunobiology. 2006; 211(5):341-50. DOI: 10.1016/j.imbio.2005.12.002. View

Zhong H, Marcus S, Li L . Microwave-assisted acid hydrolysis of proteins combined with liquid chromatography MALDI MS/MS for protein identification. J Am Soc Mass Spectrom. 2005; 16(4):471-81. DOI: 10.1016/j.jasms.2004.12.017. View

Pan S, Wang S, Jing L, Yao D . Purification and characterisation of a novel angiotensin-I converting enzyme (ACE)-inhibitory peptide derived from the enzymatic hydrolysate of Enteromorpha clathrata protein. Food Chem. 2016; 211:423-30. DOI: 10.1016/j.foodchem.2016.05.087. View

Sanjeewa K, Kim E, Son K, Jeon Y . Bioactive properties and potentials cosmeceutical applications of phlorotannins isolated from brown seaweeds: A review. J Photochem Photobiol B. 2016; 162:100-105. DOI: 10.1016/j.jphotobiol.2016.06.027. View

Choonpicharn S, Jaturasitha S, Rakariyatham N, Suree N, Niamsup H . Antioxidant and antihypertensive activity of gelatin hydrolysate from Nile tilapia skin. J Food Sci Technol. 2015; 52(5):3134-9. PMC: 4397345. DOI: 10.1007/s13197-014-1581-6. View

Bordbar S, Ebrahimpour A, Hamid A, Abdul Manap M, Anwar F, Saari N . The improvement of the endogenous antioxidant property of stone fish (Actinopyga lecanora) tissue using enzymatic proteolysis. Biomed Res Int. 2013; 2013:849529. PMC: 3613057. DOI: 10.1155/2013/849529. View

Lee T, Maruyama S . Isolation of HIV-1 protease-inhibiting peptides from thermolysin hydrolysate of oyster proteins. Biochem Biophys Res Commun. 1999; 253(3):604-8. DOI: 10.1006/bbrc.1998.9824. View

Ko S, Kim D, Jeon Y . Protective effect of a novel antioxidative peptide purified from a marine Chlorella ellipsoidea protein against free radical-induced oxidative stress. Food Chem Toxicol. 2012; 50(7):2294-302. DOI: 10.1016/j.fct.2012.04.022. View

10.

Chi C, Hu F, Wang B, Li Z, Luo H . Influence of Amino Acid Compositions and Peptide Profiles on Antioxidant Capacities of Two Protein Hydrolysates from Skipjack Tuna (Katsuwonus pelamis) Dark Muscle. Mar Drugs. 2015; 13(5):2580-601. PMC: 4446595. DOI: 10.3390/md13052580. View

11.

Kleekayai T, Harnedy P, OKeeffe M, Poyarkov A, CunhaNeves A, Suntornsuk W . Extraction of antioxidant and ACE inhibitory peptides from Thai traditional fermented shrimp pastes. Food Chem. 2015; 176:441-7. DOI: 10.1016/j.foodchem.2014.12.026. View

12.

Reyes L, Mar J, Rahman G, Seybert B, Fahrenholz T, Kingston H . Simultaneous determination of arsenic and selenium species in fish tissues using microwave-assisted enzymatic extraction and ion chromatography-inductively coupled plasma mass spectrometry. Talanta. 2009; 78(3):983-90. DOI: 10.1016/j.talanta.2009.01.003. View

13.

Agyei D, Danquah M . Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides. Biotechnol Adv. 2011; 29(3):272-7. DOI: 10.1016/j.biotechadv.2011.01.001. View

14.

Kaufmann B, Christen P . Recent extraction techniques for natural products: microwave-assisted extraction and pressurised solvent extraction. Phytochem Anal. 2002; 13(2):105-13. DOI: 10.1002/pca.631. View

15.

Je J, Park P, Byun H, Jung W, Kim S . Angiotensin I converting enzyme (ACE) inhibitory peptide derived from the sauce of fermented blue mussel, Mytilus edulis. Bioresour Technol. 2005; 96(14):1624-9. DOI: 10.1016/j.biortech.2005.01.001. View

16.

Elavarasan K, Shamasundar B, Badii F, Howell N . Angiotensin I-converting enzyme (ACE) inhibitory activity and structural properties of oven- and freeze-dried protein hydrolysate from fresh water fish (Cirrhinus mrigala). Food Chem. 2016; 206:210-6. DOI: 10.1016/j.foodchem.2016.03.047. View

17.

Smith S, Hinds Vaughan N . Assays optimized for detection and quantification of antibacterial activity in shark cell lysates under high salt conditions. Fish Shellfish Immunol. 2013; 34(5):1223-7. DOI: 10.1016/j.fsi.2013.02.001. View

18.

Pruksakorn P, Arai M, Kotoku N, Vilcheze C, Baughn A, Moodley P . Trichoderins, novel aminolipopeptides from a marine sponge-derived Trichoderma sp., are active against dormant mycobacteria. Bioorg Med Chem Lett. 2010; 20(12):3658-63. DOI: 10.1016/j.bmcl.2010.04.100. View

19.

Huang D, Li Y, Cui F, Chen J, Sun J . Purification and characterization of a novel polysaccharide-peptide complex from Clinacanthus nutans Lindau leaves. Carbohydr Polym. 2015; 137:701-708. DOI: 10.1016/j.carbpol.2015.10.102. View

20.

Wu J, Ge S, Cai Z, Liu H, Liu Y, Wang J . Purification and characterization of a gelatinolytic matrix metalloproteinase from the skeletal muscle of grass carp (Ctenopharyngodon idellus). Food Chem. 2013; 145:632-8. DOI: 10.1016/j.foodchem.2013.08.055. View