Advances in Molecular Mechanism of Cardioprotection Induced by Helium

Overview

Journal Med Gas Res

Specialties Anesthesiology
General Medicine
Pharmacology

Date 2017 Jul 27

PMID 28744366

Citations 6

Authors

Yi-Ping Ding

Ju-Yi Zhang

Dong-Xia Feng

Yan Kong

Zhuan Xu

Gang Chen

Affiliations

Soon will be listed here.

Abstract

Helium has been classified as a kind of inert gas that is not effortless to spark chemical reactions with other substances in the past decades. Nevertheless, the cognition of scientists has gradually changed accompanied with a variety of studies revealing the potential molecular mechanism underlying organ-protection induced by helium. Especially, as a non-anesthetic gas which is deficient of relevant cardiopulmonary side effects, helium conditioning is recognized as an emerging and promising approach to exert favorable effects by mimicking the cardioprotection of anesthetic gases or xenon. In this review we will summarize advances in the underlying biological mechanisms and clinical applicability with regards to the cardioprotective effects of helium.

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