Multicellular Vascularized Engineered Tissues Through User-Programmable Biomaterial Photodegradation

Overview

Journal Adv Mater

Date 2017 Jul 25

PMID 28737278

Citations 69

Authors

Christopher K Arakawa

Barry A Badeau

Ying Zheng

Cole A DeForest

Affiliations

Soon will be listed here.

Abstract

A photodegradable material-based approach to generate endothelialized 3D vascular networks within cell-laden hydrogel biomaterials is introduced. Exploiting multiphoton lithography, microchannel networks spanning nearly all size scales of native human vasculature are readily generated with unprecedented user-defined 4D control. Intraluminal channel architectures of synthetic vessels are fully customizable, providing new opportunities for next-generation microfluidics and directed cell function.

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