Instrument-free Visual Detection of Tetracycline on an Autocatalytic DNA Machine Using a Caged G-quadruplex As the Signal Reporter

Overview

Journal Chem Commun (Camb)

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2017 Jul 21

PMID 28726857

Citations 2

Authors

Junhua Chen

Shu Chen

Fengling Li

Affiliations

Soon will be listed here.

Abstract

An instrument-free visual biosensor for the amplified detection of tetracycline has been successfully constructed using an autocatalytic DNA machine as the signal amplifier and a caged G-quadruplex as the signal reporter. The assay is ultrasensitive, enabling the visual detection of trace levels of tetracycline as low as 1 pM without instrumentation.

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