Synthesis of New Tricyclic Imidazotriazepine Derivatives Condensed with Various Heterocycles

Overview

Journal Mol Divers

Date 2017 Jul 21

PMID 28726025

Authors

Tamas Foldesi

Andras Dancso

Peter Slegel

Balazs Volk

Matyas Milen

Affiliations

Soon will be listed here.

Abstract

Previously synthesized 9-aryl-5H-imidazo[2,1-d][1,2,5]triazepin-6(7H)-ones have been used as starting materials for the synthesis of three new tricyclic ring systems, where an imidazotriazepine is condensed with an imidazole, triazole or tetrazole ring. These novel compounds could be potential drug candidates for central nervous system diseases because of their closely related structure to known tricyclic derivatives with anticonvulsant activity.

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