Detection of Small-bowel Tumours with CT Enteroclysis Using Carbon Dioxide and Virtual Enteroscopy: A Preliminary Study

Overview

Journal Eur Radiol

Specialty Radiology

Date 2017 Jul 16

PMID 28710577

Citations 2

Authors

Anthony Dohan

Mourad Boudiaf

Xavier Dray

Elia Samaha

Christophe Cellier

Marine Camus

Clarisse Eveno

Raphael Dautry

Philippe Soyer

Affiliations

Soon will be listed here.

Abstract

Purpose: The aim of this prospective study was to evaluate the feasibility, tolerance and performance of virtual enteroscopy (VE) using carbon dioxide for small-bowel distension in patients with suspected small-bowel tumours (SBTs).

Patients And Methods: After IRB approval, 17 patients with suspected SBTs were prospectively included. Radiation dose was compared to 34 matched patients (2 for 1) for age, gender and body weight, who had undergone CT-enteroclysis with neutral contrast (CTE). Performance of VE was evaluated through comparison with the current standard of reference, including surgery and/or enteroscopy and/or follow-up.

Results: Tolerance was excellent in 16/17 patients (94%). The radiation dose was lower for VE than for CTE (533 ± 282 vs. 974 ± 505 mGy.cm; p = 0.002). With VE, a total of 25 polyps >5 mm in size were depicted in 12/17 patients. On a per-lesion analysis, sensitivity and positive predictive value of VE were 92.0% and 92.0%, respectively. On a per-segment analysis VE had a sensitivity and specificity of 95.0% and 87.0%, respectively.

Conclusion: Our preliminary study suggests that VE is a feasible and well-tolerated technique with high sensitivity and specificity for the diagnosis of SBT.

Key Points: • Virtual enteroscopy is feasible and well tolerated. • Virtual enteroscopy appears to be accurate for detection of small-bowel tumours. • Sensitivity and PPV of virtual enteroscopy is 92.0% and 92.0%. • Radiation dose is lower with virtual enteroscopy compared to MDCT-enteroclysis.

Citing Articles

Computed tomography enteroclysis combined with double-balloon endoscopy is beneficial to the diagnosis of small bowel submucosal tumors.

Wang P, Dong W, Zhao L, Liu Z, Yang F, Tan X Am J Transl Res. 2023; 15(4):2836-2842.

PMID: 37193180 PMC: 10182530.

CT Texture Analysis for Preoperative Identification of Lymphoma from Other Types of Primary Small Bowel Malignancies.

Liu S, Zhang C, Liu R, Li S, Xu F, Liu X Biomed Res Int. 2021; 2021:5519144.

PMID: 33884262 PMC: 8041543. DOI: 10.1155/2021/5519144.

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