Difficult-to-Detect Low-Grade Infections Responsible for Poor Outcomes in Total Knee Arthroplasty
Overview
Affiliations
In this article, we present the case of a patient with a stiff, painful knee after total knee arthroplasty, and with erythrocyte sedimentation rate, C-reactive protein level, and synovial fluid analysis within normal limits. Open biopsy for cultures showed Propionibacterium acnes prosthetic joint infection, which was successfully treated with 2-stage revision and intravenous antibiotics.
Dyslipidaemia is associated with Cutibacterium acnes hip and knee prosthetic joint infection.
Reynolds A, Valles K, Wang D, Vyas P, Regal S, Garay M Int Orthop. 2023; 48(4):899-904.
PMID: 38157039 DOI: 10.1007/s00264-023-06066-4.
Why do knees after total knee arthroplasty fail in different parts of the world?.
Mathis D, Hirschmann M J Orthop. 2021; 23:52-59.
PMID: 33456216 PMC: 7797486. DOI: 10.1016/j.jor.2020.12.007.
Li Z, Hou Y, Zhang B, Chen Y, Wang Q, Wang K Orthop Surg. 2018; 10(3):235-240.
PMID: 30152610 PMC: 6594504. DOI: 10.1111/os.12394.
Paish H, Kalson N, Smith G, Pons A, Baldock T, Smith N Am J Pathol. 2017; 188(3):696-714.
PMID: 29248462 PMC: 5842035. DOI: 10.1016/j.ajpath.2017.11.007.