Rosette-forming Glioneuronal Tumor: Rare Case Presented with Spontaneous Disappearance of Contrast Enhancement

Overview

Journal NMC Case Rep J

Specialty Neurology

Date 2017 Jul 1

PMID 28663967

Citations 4

Authors

Shinya Haryu

Ryuta Saito

Masayuki Kanamori

Yukihiko Sonoda

Toshihiro Kumabe

Mika Watanabe

Faruk Tonga

Teiji Tominaga

Affiliations

Soon will be listed here.

Abstract

This report presents rosette-forming glioneuronal tumor (RGNT) of the tectum in a 24-year-old woman in whom spontaneous disappearance of contrast enhancement (CE) on magnetic resonance (MR) imaging was observed during 9-year follow-up period before therapeutic intervention. MR imaging obtained 9 years ago when she first visited local hospital with headaches showed a mass of the brain stem with CE. Follow-up MR imaging showed disappearance of CE without tumor growth. Nine years later, she was admitted to our hospital with headache and nausea, due to obstructive hydrocephalus. She underwent endoscopic third ventriculostomy (ETV) and tumor biopsy. Histological study revealed RGNT. To our knowledge, this is the first report presenting that the RGNT may show spontaneous disappearance of CE without tumor growth. It is unclear what this phenomenon means, however, knowledge of this phenomenon may be helpful for correct diagnosis and for follow up of RGNT.

Citing Articles

Molecular analyses of rosette-forming glioneuronal tumor of the midbrain tegmentum: A report of two cases and a review of the FGFR1 status in unusual tumor locations.

Handa H, Shibahara I, Nakano Y, Inukai M, Sato S, Hide T Surg Neurol Int. 2022; 13:213.

PMID: 35673672 PMC: 9168299. DOI: 10.25259/SNI_55_2022.

Rosette-Forming Glioneuronal Tumor of the Fourth Ventricle: A Case of Relapse Treated with Proton Beam Therapy.

Cacchione A, Mastronuzzi A, Carai A, Colafati G, Diomedi-Camassei F, Marrazzo A Diagnostics (Basel). 2021; 11(5).

PMID: 34069450 PMC: 8159123. DOI: 10.3390/diagnostics11050903.

Rosette-forming glioneuronal tumor: an illustrative case and a systematic review.

Wilson C, Chakraborty A, Pelargos P, Shi H, Milton C, Sung S Neurooncol Adv. 2020; 2(1):vdaa116.

PMID: 33134925 PMC: 7586144. DOI: 10.1093/noajnl/vdaa116.

A case of a rosette-forming glioneuronal tumor arising from the pons with disappearance of contrast enhancement.

Tanaka F, Matsukawa M, Kogue R, Umino M, Maeda M, Uchida K Radiol Case Rep. 2019; 14(8):899-902.

PMID: 31193570 PMC: 6535692. DOI: 10.1016/j.radcr.2019.05.011.

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