A Liver-specific Gene Expression Panel Predicts the Differentiation Status of in Vitro Hepatocyte Models

Overview

Journal Hepatology

Specialty Gastroenterology

Date 2017 Jun 23

PMID 28640507

Citations 33

Authors

Dae-Soo Kim

Jea-Woon Ryu

Mi-Young Son

Jung-Hwa Oh

Kyung-Sook Chung

Sugi Lee

Jeong-Ju Lee

Jun-Ho Ahn

Ju-Sik Min

Jiwon Ahn

Hyun Mi Kang

Janghwan Kim

Cho-Rok Jung

Nam-Soon Kim

Hyun-Soo Cho

Affiliations

Soon will be listed here.

Abstract

Conclusion: Our study describes a quantitative and predictive model for differentiated samples, particularly liver-specific cells or organoids; and this model can be further expanded to various tissue-specific organoids; our LiGEP can provide useful information and insights regarding the differentiation status of in vitro liver models. (Hepatology 2017;66:1662-1674).

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