Morphology and Distribution of Tyrosine Hydroxylase-like Immunoreactive Neurons in the Cat Retina

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 1985 Sep 1

PMID 2863820

Citations 19

Authors

C W OYSTER

E S TAKAHASHI

M Cilluffo

N C Brecha

Affiliations

Soon will be listed here.

Abstract

In cat retina, antisera directed against tyrosine hydroxylase (tyrosine 3-monooxygenase; EC 1.14.16.2) labeled three morphologically distinct classes of neurons; amacrine cells, displaced amacrine cells, and interplexiform cells. These three cell populations differed not only in their morphologies but also in their numbers, densities, and retinal distributions. Insofar as tyrosine hydroxylase-like immunoreactivity is associated with dopaminergic neurons, these observations suggest that the dopamine system in cat retina is morphologically heterogeneous and that the cat retina contains functional subdivisions based on the different distributions of specific cell populations.

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References

Kramer S . Dopamine: A retinal neurotransmitter. I. Retinal uptake, storage, and light-stimulated release of H3-dopamine in vivo. Invest Ophthalmol. 1971; 10(6):438-52. View

Bishop P, Kozak W, VAKKUR G . Some quantitative aspects of the cat's eye: axis and plane of reference, visual field co-ordinates and optics. J Physiol. 1962; 163:466-502. PMC: 1359720. DOI: 10.1113/jphysiol.1962.sp006990. View

BOYCOTT B, Dowling J, Fisher S, Kolb H, Laties A . Interplexiform cells of the mammalian retina and their comparison with catecholamine-containing retinal cells. Proc R Soc Lond B Biol Sci. 1975; 191(1104):353-68. DOI: 10.1098/rspb.1975.0133. View

Hughes A . A supplement to the cat schematic eye. Vision Res. 1976; 16(2):149-54. DOI: 10.1016/0042-6989(76)90091-2. View

Dowling J, Ehinger B . The interplexiform cell system. I. Synapses of the dopaminergic neurons of the goldfish retina. Proc R Soc Lond B Biol Sci. 1978; 201(1142):7-26. DOI: 10.1098/rspb.1978.0030. View

Stone J . The number and distribution of ganglion cells in the cat's retina. J Comp Neurol. 1978; 180(4):753-71. DOI: 10.1002/cne.901800407. View

TORK I, Stone J . Morphology of catecholamine-containing amacrine cells in the cat's retina, as seen in retinal whole mounts. Brain Res. 1979; 169(2):261-73. DOI: 10.1016/0006-8993(79)91029-1. View

Nakamura Y, McGuire B, Sterling P . Interplexiform cell in cat retina: identification by uptake of gamma-[3H]aminobutyric acid and serial reconstruction. Proc Natl Acad Sci U S A. 1980; 77(1):658-61. PMC: 348334. DOI: 10.1073/pnas.77.1.658. View

Dowling J, Ehinger B, Floren I . Fluorescence and electron microscopical observations on the amine-accumulating neurons of the cebus monkey retina. J Comp Neurol. 1980; 192(4):665-85. DOI: 10.1002/cne.901920404. View

10.

Negishi K, Nakamura T, Hayashi T . Spatial density of catecholaminergic cells in the carp retina. Exp Eye Res. 1980; 31(6):711-9. DOI: 10.1016/s0014-4835(80)80055-8. View

11.

Stephens J, Masserano J, Vulliet P, WEINER N, Nakane P . Immunocytochemical localization of tyrosine hydroxylase in rat adrenal medulla by the peroxidase labeled antibody method: effects of enzyme activation on ultrastructural distribution of the enzyme. Brain Res. 1981; 209(2):339-54. DOI: 10.1016/0006-8993(81)90158-x. View

12.

Pourcho R . Autoradiographic localization of [3H]muscimol in the cat retina. Brain Res. 1981; 215(1-2):187-99. DOI: 10.1016/0006-8993(81)90501-1. View

13.

Kolb H, Nelson R, Mariani A . Amacrine cells, bipolar cells and ganglion cells of the cat retina: a Golgi study. Vision Res. 1981; 21(7):1081-1114. DOI: 10.1016/0042-6989(81)90013-4. View

14.

Nguyen-Legros J, Berger B, Vigny A, Alvarez C . Tyrosine hydroxylase-like immunoreactive interplexiform cells in the rat retina. Neurosci Lett. 1981; 27(3):255-9. DOI: 10.1016/0304-3940(81)90439-0. View

15.

Pourcho R . Dopaminergic amacrine cells in the cat retina. Brain Res. 1982; 252(1):101-9. DOI: 10.1016/0006-8993(82)90982-9. View

16.

Amthor F, OYSTER C, TAKAHASHI E . Quantitative morphology of rabbit retinal ganglion cells. Proc R Soc Lond B Biol Sci. 1983; 217(1208):341-55. DOI: 10.1098/rspb.1983.0014. View

17.

Thier P, Alder V . Action of iontophoretically applied dopamine on cat retinal ganglion cells. Brain Res. 1984; 292(1):109-21. DOI: 10.1016/0006-8993(84)90895-3. View

18.

Brecha N, OYSTER C, TAKAHASHI E . Identification and characterization of tyrosine hydroxylase immunoreactive amacrine cells. Invest Ophthalmol Vis Sci. 1984; 25(1):66-70. View

19.

Nguyen-Legros J, Botteri C, Phuc L, Vigny A, Gay M . Morphology of primate's dopaminergic amacrine cells as revealed by TH-like immunoreactivity on retinal flat-mounts. Brain Res. 1984; 295(1):145-53. DOI: 10.1016/0006-8993(84)90825-4. View

20.

Versaux-Botteri C, Nguyen-Legros J, Vigny A, Raoux N . Morphology, density and distribution of tyrosine hydroxylase-like immunoreactive cells in the retina of mice. Brain Res. 1984; 301(1):192-7. DOI: 10.1016/0006-8993(84)90423-2. View