A Case of Renal Dysfunction Caused by Pelvic Organ Prolapse

Overview

Journal CEN Case Rep

Specialty Nephrology

Date 2017 Jun 22

PMID 28634833

Citations 5

Authors

Ai Miyagi

Yusuke Inaguma

Tomoaki Tokoyoda

Takashi Nakajima

Ryozo Sezaki

Tetsuya Matsukawa

Affiliations

Soon will be listed here.

Abstract

Pelvic organ prolapse (POP) is the descent of pelvic organs through the vagina, and sometimes causes hydronephrosis. Although the association between POP and hydronephrosis has long been recognized, severe hydronephrosis and renal dysfunction are rarely seen. We report a case of 66-year-old woman who had a vaginal delivery presented with externalized uterine and bladder prolapse during the previous 2 years. She had a 3-day history of hypophagia and vomiting, and laboratory analysis resulted in serum creatinine of 5.75 mg/dL and blood urea of 78.1 mg/dL. The patient was treated urgently with vaginal pessary to return the uterine and bladder into the pelvis. After 2 weeks, her serum creatinine dropped to 3.66 mg/dL, but chronic renal failure persisted. Hydronephrosis caused by POP may lead to renal dysfunction and can advance to irreversible renal damage if left untreated. Important is early evaluation of renal function and images of the kidney and ureter.

Citing Articles

Acute Renal Failure Caused by Undiagnosed Pelvic Organ Prolapse in a Postmenopausal Woman: A Diagnosis Not to Be Missed.

Khaleel M, Ayyad M, Albandak M, Khalil N, M A Abu Taleb S Cureus. 2023; 15(9):e44513.

PMID: 37790056 PMC: 10544584. DOI: 10.7759/cureus.44513.

A serious consequence of pelvic organ prolapse: Hydroureteronephrosis.

Serin A, Birge O Int Urogynecol J. 2023; 34(9):2147-2154.

PMID: 37010544 DOI: 10.1007/s00192-023-05519-z.

Pelvic organ prolapse and uterine preservation: a cohort study (POP-UP study).

Gagyor D, Kalis V, Smazinka M, Rusavy Z, Pilka R, Ismail K BMC Womens Health. 2021; 21(1):72.

PMID: 33596878 PMC: 7890869. DOI: 10.1186/s12905-021-01208-5.

Traditional Chinese medicine decreases the obstructive uropathy risk in uterovaginal prolapse: A nationwide population-based study.

Chang Y, Chen W, Chiang J, Su Y, Tsai K, Man K Medicine (Baltimore). 2018; 97(38):e12369.

PMID: 30235697 PMC: 6160251. DOI: 10.1097/MD.0000000000012369.

Primary vaginal squamous cell carcinoma with bladder involvement in uterine prolapsed patient: Case report.

Fedus T, Ras R, Ksiazek M, Filipowska J, Kaznowska E, Skret A Medicine (Baltimore). 2018; 96(50):e8993.

PMID: 29390294 PMC: 5815706. DOI: 10.1097/MD.0000000000008993.

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