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The Florence Statement on Triclosan and Triclocarban

Abstract

documents a consensus of more than 200 scientists and medical professionals on the hazards of and lack of demonstrated benefit from common uses of triclosan and triclocarban. These chemicals may be used in thousands of personal care and consumer products as well as in building materials. Based on extensive peer-reviewed research, this statement concludes that triclosan and triclocarban are environmentally persistent endocrine disruptors that bioaccumulate in and are toxic to aquatic and other organisms. Evidence of other hazards to humans and ecosystems from triclosan and triclocarban is presented along with recommendations intended to prevent future harm from triclosan, triclocarban, and antimicrobial substances with similar properties and effects. Because antimicrobials can have unintended adverse health and environmental impacts, they should only be used when they provide an evidence-based health benefit. Greater transparency is needed in product formulations, and before an antimicrobial is incorporated into a product, the long-term health and ecological impacts should be evaluated. https://doi.org/10.1289/EHP1788.

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References
1.
Fiss E, Rule K, Vikesland P . Formation of chloroform and other chlorinated byproducts by chlorination of triclosan-containing antibacterial products. Environ Sci Technol. 2007; 41(7):2387-94. DOI: 10.1021/es062227l. View

2.
Philippat C, Botton J, Calafat A, Ye X, Charles M, Slama R . Prenatal exposure to phenols and growth in boys. Epidemiology. 2014; 25(5):625-35. PMC: 4724208. DOI: 10.1097/EDE.0000000000000132. View

3.
Hu J, Raikhel V, Gopalakrishnan K, Fernandez-Hernandez H, Lambertini L, Manservisi F . Effect of postnatal low-dose exposure to environmental chemicals on the gut microbiome in a rodent model. Microbiome. 2016; 4(1):26. PMC: 4906585. DOI: 10.1186/s40168-016-0173-2. View

4.
Drury B, Scott J, Rosi-Marshall E, Kelly J . Triclosan exposure increases triclosan resistance and influences taxonomic composition of benthic bacterial communities. Environ Sci Technol. 2013; 47(15):8923-30. DOI: 10.1021/es401919k. View

5.
Zheng G, Leung A, Jiao L, Wong M . Polychlorinated dibenzo-p-dioxins and dibenzofurans pollution in China: sources, environmental levels and potential human health impacts. Environ Int. 2008; 34(7):1050-61. DOI: 10.1016/j.envint.2008.02.011. View