Risk of Dementia in Adults With ADHD: A Nationwide, Population-Based Cohort Study in Taiwan

Overview

Journal J Atten Disord

Publisher Sage Publications

Specialty Psychiatry

Date 2017 Jun 21

PMID 28629260

Citations 22

Authors

Nian-Sheng Tzeng

Chi-Hsiang Chung

Fu-Huang Lin

Chin-Bin Yeh

San-Yuan Huang

Ru-Band Lu

Hsin-An Chang

Yu-Chen Kao

Hui-Wen Yeh

Wei-Shan Chiang

Yu-Ching Chou

Chang-Huei Tsao

Yung-Fu Wu

Wu-Chien Chien

Affiliations

Soon will be listed here.

Abstract

Objective: This study aimed to investigate the association between adults with ADHD and the risk of developing dementia.

Method: Utilizing National Health Insurance Research Database of Taiwan, ADHD patients were identified and compared with age- and gender-matched controls (1:3).

Results: Of the study participants, 37 (5.48%) developed dementia compared with 81 (4.0%) in the control group. Cox proportional hazards regression analysis revealed that the study participants were more likely to develop dementia. The crude hazard ratio (HR) is 3.418 (95% confidence interval [CI] = [2.289, 5.106], p < .001), and adjusted HR is 4.008 (95% CI = [2.526, 6.361], p < .001) in risk of developing dementia after adjusted for age, gender, comorbidities, geographical area of residence, urbanization level of residence, and monthly income.

Conclusion: Adults with ADHD have a 3.4-fold risk of developing dementia, and other large or national data sets should be explored to support the current findings.

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Adult Attention-Deficit/Hyperactivity Disorder and the Risk of Dementia.

Levine S, Rotstein A, Kodesh A, Sandin S, Lee B, Weinstein G JAMA Netw Open. 2023; 6(10):e2338088.

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