Radiation-Induced Oral Mucositis

Overview

Journal Front Oncol

Specialty Oncology

Date 2017 Jun 8

PMID 28589080

Citations 133

Authors

Osama Muhammad Maria

Nicoletta Eliopoulos

Thierry Muanza

Affiliations

Soon will be listed here.

Abstract

Radiation-induced oral mucositis (RIOM) is a major dose-limiting toxicity in head and neck cancer patients. It is a normal tissue injury caused by radiation/radiotherapy (RT), which has marked adverse effects on patient quality of life and cancer therapy continuity. It is a challenge for radiation oncologists since it leads to cancer therapy interruption, poor local tumor control, and changes in dose fractionation. RIOM occurs in 100% of altered fractionation radiotherapy head and neck cancer patients. In the United Sates, its economic cost was estimated to reach 17,000.00 USD per patient with head and neck cancers. This review will discuss RIOM definition, epidemiology, impact and side effects, pathogenesis, scoring scales, diagnosis, differential diagnosis, prevention, and treatment.

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