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Improving Nutrition Through Biofortification: A Review of Evidence from HarvestPlus, 2003 Through 2016

Overview
Journal Glob Food Sec
Publisher Elsevier
Date 2017 Jun 6
PMID 28580239
Citations 204
Authors
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Abstract

Biofortification is a feasible and cost-effective means of delivering micronutrients to populations that may have limited access to diverse diets and other micronutrient interventions. Since 2003, HarvestPlus and its partners have demonstrated that this agriculture-based method of addressing micronutrient deficiency through plant breeding works. More than 20 million people in farm households in developing countries are now growing and consuming biofortified crops. This review summarizes key evidence and discusses delivery experiences, as well as farmer and consumer adoption. Given the strength of the evidence, attention should now shift to an action-oriented agenda for scaling biofortification to improve nutrition globally. To reach one billion people by 2030, there are three key challenges: 1) mainstreaming biofortified traits into public plant breeding programs; 2) building consumer demand; and 3) integrating biofortification into public and private policies, programs, and investments. While many building blocks are in place, institutional leadership is needed to continue to drive towards this ambitious goal.

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References
1.
Haskell M, Jamil K, Hassan F, Peerson J, Hossain M, Fuchs G . Daily consumption of Indian spinach (Basella alba) or sweet potatoes has a positive effect on total-body vitamin A stores in Bangladeshi men. Am J Clin Nutr. 2004; 80(3):705-14. DOI: 10.1093/ajcn/80.3.705. View

2.
Gannon B, Kaliwile C, Arscott S, Schmaelzle S, Chileshe J, Kalungwana N . Biofortified orange maize is as efficacious as a vitamin A supplement in Zambian children even in the presence of high liver reserves of vitamin A: a community-based, randomized placebo-controlled trial. Am J Clin Nutr. 2014; 100(6):1541-50. PMC: 4232019. DOI: 10.3945/ajcn.114.087379. View

3.
Bouis H, Hotz C, McCLAFFERTY B, Meenakshi J, Pfeiffer W . Biofortification: a new tool to reduce micronutrient malnutrition. Food Nutr Bull. 2011; 32(1 Suppl):S31-40. DOI: 10.1177/15648265110321S105. View

4.
Talsma E, Brouwer I, Verhoef H, Mbera G, Mwangi A, Demir A . Biofortified yellow cassava and vitamin A status of Kenyan children: a randomized controlled trial. Am J Clin Nutr. 2015; 103(1):258-67. DOI: 10.3945/ajcn.114.100164. View

5.
Palmer A, Healy K, Barffour M, Siamusantu W, Chileshe J, Schulze K . Provitamin A Carotenoid-Biofortified Maize Consumption Increases Pupillary Responsiveness among Zambian Children in a Randomized Controlled Trial. J Nutr. 2016; 146(12):2551-2558. DOI: 10.3945/jn.116.239202. View