Venlafaxine Intoxication with Development of Takotsubo Cardiomyopathy: Successful Use of Extracorporeal Life Support, Intravenous Lipid Emulsion and CytoSorb®

Overview

Journal Int J Artif Organs

Date 2017 Jun 3

PMID 28574114

Citations 15

Authors

Ines Schroeder

Michael Zoller

Matthias Angstwurm

Felix Kur

Lorenz Frey

Affiliations

Soon will be listed here.

Abstract

We describe a young patient who ingested 18 g (240 times the daily therapeutic dose) of venlafaxine in a suicide attempt. She developed severe cardiomyopathy in a takotsubo distribution causing cardiogenic shock and multi-organ dysfunction syndrome (MODS). She was successfully treated with intravenous lipid emulsion (ILE), extracorporeal life support (ECLS) and CytoSorb®. This is remarkable as, to the best of the authors' knowledge, this is the highest amount of venlafaxine intake seen in the literature with a nonfatal outcome.

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