» Articles » PMID: 28541989

Irritable Bowel Syndrome

Overview
Journal Am J Nurs
Specialty Nursing
Date 2017 May 26
PMID 28541989
Citations 28
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Abstract

: Irritable bowel syndrome (IBS) is a common, chronic gastrointestinal (GI) condition characterized by disturbances in bowel habits and abdominal pain in the absence of known organic pathology. IBS reduces quality of life and is costly to treat. It is diagnosed using the symptom-based Rome criteria for functional GI disorders, which was recently updated and released as Rome IV. Both physiologic and psychological variables play a role in the etiology of IBS and perpetuate symptoms. Although research has shed light on IBS pathophysiology, therapeutic interventions remain symptom driven, employing both pharmacologic and nonpharmacologic approaches. Here, the authors review the epidemiology and pathophysiology of IBS, summarize diagnostic and treatment strategies, and discuss implications for nursing practice.

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References
1.
Jones M, Chey W, Singh S, Gong H, Shringarpure R, Hoe N . A biomarker panel and psychological morbidity differentiates the irritable bowel syndrome from health and provides novel pathophysiological leads. Aliment Pharmacol Ther. 2014; 39(4):426-37. DOI: 10.1111/apt.12608. View

2.
Inadomi J, Fennerty M, Bjorkman D . Systematic review: the economic impact of irritable bowel syndrome. Aliment Pharmacol Ther. 2003; 18(7):671-82. DOI: 10.1046/j.1365-2036.2003.t01-1-01736.x. View

3.
Fichna J, Storr M . Brain-Gut Interactions in IBS. Front Pharmacol. 2012; 3:127. PMC: 3389673. DOI: 10.3389/fphar.2012.00127. View

4.
Stasi C, Rosselli M, Bellini M, Laffi G, Milani S . Altered neuro-endocrine-immune pathways in the irritable bowel syndrome: the top-down and the bottom-up model. J Gastroenterol. 2012; 47(11):1177-85. DOI: 10.1007/s00535-012-0627-7. View

5.
Halland M, Saito Y . Irritable bowel syndrome: new and emerging treatments. BMJ. 2015; 350:h1622. DOI: 10.1136/bmj.h1622. View