Enhancement of Enzyme-catalyzed Production of Reactive Oxygen Species by Suspensions of "crocidolite" Asbestos Fibres

Overview

Journal Free Radic Res Commun

Specialty Chemistry

Date 1986 Jan 1

PMID 2851503

Citations 2

Authors

E F Elstner

W Schutz

G Vogl

Affiliations

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Abstract

Ethylene release from methylthio-ketobutyric acid is an indicator for activated oxygen species of the OH.-radical type. Xanthine oxidase plus xanthine or diaphorase in the presence of NADH and juglone produce OH.-type oxy-radicals. The production of reactive oxygen species in these enzymatic systems is enhanced by "crocidolite" asbestos fibres.

Citing Articles

AKT/mTOR and c-Jun N-terminal kinase signaling pathways are required for chrysotile asbestos-induced autophagy.

Lin Z, Liu T, Kamp D, Wang Y, He H, Zhou X Free Radic Biol Med. 2014; 72:296-307.

PMID: 24735948 PMC: 4075764. DOI: 10.1016/j.freeradbiomed.2014.04.004.

Cooperative stimulation by sulfite and crocidolite asbestos fibres of enzyme catalyzed production of reactive oxygen species.

Elstner E, Schutz W, Vogl G Arch Toxicol. 1988; 62(6):424-7.

PMID: 2854963 DOI: 10.1007/BF00288344.