» Articles » PMID: 28465788

Type 2 Diabetes and Quality of Life

Overview
Specialty Endocrinology
Date 2017 May 4
PMID 28465788
Citations 210
Authors
Affiliations
Soon will be listed here.
Abstract

It is true that a primary goal of diabetes early diagnosis and treatment is quality of life (QoL). The term QoL is still confusing but it is agreed that it composes of four components: The physical component, mental, cogitative component, psychological and social component. Many articles have been written addressing those four components. During the last five years 15500 articles and reviews have been written addressing diabetes and coronary arterial disease, 16100 addressing diabetes and renal function, 28900 addressing diabetes and retinopathy, 16800 addressing diabetic foot ulcers and other 26300 addressing diabetic neuropathy. Moreover 17200 articles are dealing with diabetic sexual dysfunction, 24500 with the correlation of diabetes and depression 17500 about diabetes and dementia, only 1 about diabetes and family functioning and 1950000 about diabetes and QoL, indicating the worldwide interest. In order to confront this metabolic anomaly and its consequences, researchers developed numerous generic and disease specific psychometric tools. With the aid of those psychometric tools the scientific community has started to realize the gruesome effect of diabetes on patients' lives. Diabetic's QoL becomes worse when complications start to develop or comorbidities coexist. Dominant amongst complications, in health-related quality of life (HRQoL) lowering, but not related to risk factors (genetic, the weight of birth, or others) is coronary arterial disease followed by renal failure, blindness, and the combination of micro- and macro-vascular complications and in some studies by sexual dysfunction. Moreover many are the comorbidities which deteriorate further the effect of diabetes in a patient life. Among them obesity, hypertension, dyslipidemia, depression, arthritis are the most common. Most intriguing field for research is the interaction of diabetes and depression and in some cases the progression to dementia. Many aspects and combinations of actions are under researchers' microscope regarding the improvement of HRQoL scores. Until now, the studies performed, have demonstrated little to moderate benefit. More of them are needed to draw safe conclusions on the topic of the best combination of actions to optimize the HRQoL scores.

Citing Articles

Effects of Endurance Training and Chlorogenic Acid on Oxidative and Nitrosative Stress Markers in Prediabetic Male Mice.

Ghasemi Pour S, Marandi S Int J Prev Med. 2025; 16:5.

PMID: 40046694 PMC: 11878644. DOI: 10.4103/ijpvm.ijpvm_122_23.


Web-Based, Algorithm-Guided Insulin Titration in Insulin-Treated Type 2 Diabetes: Pre-Post Intervention Study.

Thiagarajan N, Tan H, Rama Chandran S, Lee P, Chin Y, Zeng W JMIR Form Res. 2025; 9:e68914.

PMID: 39924297 PMC: 11830485. DOI: 10.2196/68914.


Socioeconomic and ethnic inequalities increase the risk of type 2 diabetes: an analysis of NHS health check attendees in Birmingham.

Au-Yeung C, Ellis D, Dallaway A, Riley J, Varney J, Howell-Jones R Front Public Health. 2024; 12:1477418.

PMID: 39664526 PMC: 11631903. DOI: 10.3389/fpubh.2024.1477418.


Social/Emotional Health, Mental Health and Quality of Life among Adults with Comorbid Diabetes and Hypertension: A Population-based Cross-sectional Study.

Misra R, Nayeem S J Appalach Health. 2024; 6(1-2):117-132.

PMID: 39640239 PMC: 11617023. DOI: 10.13023/jah.0601.08.


Physicians' Perspectives on Health-Related Quality of Life and Mental Health Aspects of People with Type 2 Diabetes Mellitus: A Cross-Sectional Study in Jeddah, Saudi Arabia.

Alzahrani O, Fletcher J, Hitos K Diabetes Metab Syndr Obes. 2024; 17:4287-4297.

PMID: 39564448 PMC: 11575439. DOI: 10.2147/DMSO.S491491.


References
1.
Pereira M, Palming J, Rizell M, Aureliano M, Carvalho E, Svensson M . The immunosuppressive agents rapamycin, cyclosporin A and tacrolimus increase lipolysis, inhibit lipid storage and alter expression of genes involved in lipid metabolism in human adipose tissue. Mol Cell Endocrinol. 2012; 365(2):260-9. DOI: 10.1016/j.mce.2012.10.030. View

2.
Wee H, Cheung Y, Li S, Fong K, Thumboo J . The impact of diabetes mellitus and other chronic medical conditions on health-related Quality of Life: is the whole greater than the sum of its parts?. Health Qual Life Outcomes. 2005; 3:2. PMC: 548134. DOI: 10.1186/1477-7525-3-2. View

3.
Solli O, Stavem K, Kristiansen I . Health-related quality of life in diabetes: The associations of complications with EQ-5D scores. Health Qual Life Outcomes. 2010; 8:18. PMC: 2829531. DOI: 10.1186/1477-7525-8-18. View

4.
Dominick K, Ahern F, Gold C, Heller D . Relationship of health-related quality of life to health care utilization and mortality among older adults. Aging Clin Exp Res. 2003; 14(6):499-508. DOI: 10.1007/BF03327351. View

5.
DeSalvo K, Bloser N, Reynolds K, He J, Muntner P . Mortality prediction with a single general self-rated health question. A meta-analysis. J Gen Intern Med. 2005; 21(3):267-75. PMC: 1828094. DOI: 10.1111/j.1525-1497.2005.00291.x. View