Na+,K+-ATPase: Tissue-specific Expression of Genes Coding for Alpha-subunit in Diverse Human Tissues

Overview

Journal FEBS Lett

Specialty Biochemistry

Date 1988 Oct 24

PMID 2846349

Citations 3

Authors

E D Sverdlov

N S Akopyanz

K E Petrukhin

N E Broude

G S Monastyrskaya

N N Modyanov

Affiliations

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Abstract

The expression of genes coding for alpha and alpha III isoforms of Na+,K+-ATPase alpha-subunit has been studied in human kidney, brain, thyroid and liver cells. The expression was shown to be subjected to a tissue-specific control and also depended on the developmental stage. The tissue-specific expression of genes coding for different isoforms of the catalytic subunit of Na+,K+-ATPase perhaps may be attributed to various functions of proteins belonging to this family.

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