Origin and Direction of Replication in Mitochondrial Plasmid DNAs of Broad Bean, Vicia Faba

Overview

Journal Curr Genet

Specialty Genetics

Date 1988 Aug 1

PMID 2846190

Citations 13

Authors

J A Wahleithner

D R WOLSTENHOLME

Affiliations

Soon will be listed here.

Abstract

Broad bean (Vicia faba) mitochondrial DNA (mtDNA) includes three circular plasmids: mt-plasmid 1 (1,704 ntp), mt-plasmid 2 (1,695 ntp) and mt-plasmid 3 (1,476 ntp). Partially replicated circular forms of these mt-plasmids have been observed in electron microscope preparations. Restriction enzymes that cleave either mt-plasmid 2 (but not mt-plasmids 1 and 3) or mt-plasmid 3 (but not mt-plasmids 1 and 2) were used to generate linear forms of partially replicated mt-plasmid 2 and mt-plasmid 3 molecules. Analyses of these linearized replicative intermediates, observed by electron microscopy, indicated that in both mt-plasmid 2 and mt-plasmid 3 replication originates at a specific location and proceeds in the same, single direction around the molecules. The replication origins of mt-plasmid 2 and mt-plasmid 3 map close to sequences that can fold into hairpin structures.

Citing Articles

Mitochondrial Genome Sequence of the Legume Vicia faba.

Negruk V Front Plant Sci. 2013; 4:128.

PMID: 23675376 PMC: 3646248. DOI: 10.3389/fpls.2013.00128.

Unique features of the mitochondrial rolling circle-plasmid mp1 from the higher plant Chenopodium album (L.).

Backert S, Meissner K, Borner T Nucleic Acids Res. 1997; 25(3):582-89.

PMID: 9016599 PMC: 146482. DOI: 10.1093/nar/25.3.582.

Rolling-circle replication of mitochondrial DNA in the higher plant Chenopodium album (L.).

Backert S, Dorfel P, Lurz R, Borner T Mol Cell Biol. 1996; 16(11):6285-94.

PMID: 8887658 PMC: 231631. DOI: 10.1128/MCB.16.11.6285.

Electron microscopic investigation of mitochondrial DNA from Chenopodium album (L.).

Backert S, Lurz R, Borner T Curr Genet. 1996; 29(5):427-36.

PMID: 8625421 DOI: 10.1007/BF02221510.

Linear mitochondrial genome organization in vivo in the genus Pythium.

Martin F Curr Genet. 1995; 28(3):225-34.

PMID: 8529268 DOI: 10.1007/BF00309781.

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