» Articles » PMID: 28447316

Mining and Environmental Health Disparities in Native American Communities

Overview
Date 2017 Apr 28
PMID 28447316
Citations 78
Authors
Affiliations
Soon will be listed here.
Abstract

Purpose Of Review: More than a century of hard rock mining has left a legacy of >160,000 abandoned mines in the Western USA that are home to the majority of Native American lands. This article describes how abrogation of treaty rights, ineffective policies, lack of infrastructure, and a lack of research in Native communities converge to create chronic exposure, ill-defined risks, and tribal health concerns.

Recent Findings: Recent results show that Native Americans living near abandoned uranium mines have an increased likelihood for kidney disease and hypertension, and an increased likelihood of developing multiple chronic diseases linked to their proximity to the mine waste and activities bringing them in contact with the waste. Biomonitoring confirms higher than expected exposure to uranium and associated metals in the waste in adults, neonates, and children in these communities. These sites will not be cleaned up for many generations making it critical to understand and prioritize exposure-toxicity relationships in Native populations to appropriately allocate limited resources to protect health. Recent initiatives, in partnership with Native communities, recognize these needs and support development of tribal research capacity to ensure that research respectful of tribal culture and policies can address concerns in the future. In addition, recognition of the risks posed by these abandoned sites should inform policy change to protect community health in the future.

Citing Articles

Waves of change: A systematic literature review of water and environmental justice research.

Canfield K, Cato A, Torso K, Mulvaney K Hydrol Sci J. 2025; 69(1):120-138.

PMID: 39996026 PMC: 11848728. DOI: 10.1080/02626667.2023.2280679.


Zinc as a Mechanism-Based Strategy for Mitigation of Metals Toxicity.

Hudson L, Dashner-Titus E, MacKenzie D Curr Environ Health Rep. 2025; 12(1):5.

PMID: 39827326 PMC: 11742765. DOI: 10.1007/s40572-025-00474-x.


Ecosystem Drivers of Freshwater Mercury Bioaccumulation Are Context-Dependent: Insights from Continental-Scale Modeling.

Kotalik C, Willacker J, Wesner J, Johnson B, Flanagan Pritz C, Nelson S Environ Sci Technol. 2025; 59(3):1780-1789.

PMID: 39812405 PMC: 11780732. DOI: 10.1021/acs.est.4c07280.


Relationship Between Urinary Uranium and Cardiac Geometry and Left Ventricular Function: The Strong Heart Study.

Lieberman-Cribbin W, Martinez-Morata I, Domingo-Relloso A, Umans J, Cole S, OLeary M JACC Adv. 2024; 3(12):101408.

PMID: 39640231 PMC: 11617505. DOI: 10.1016/j.jacadv.2024.101408.


Impact of Structural Racism and Social Determinants of Health on Disparities in Breast Cancer Mortality.

Falcone M, Salhia B, Halbert C, Roussos Torres E, Stewart D, Stern M Cancer Res. 2024; 84(23):3924-3935.

PMID: 39356624 PMC: 11611670. DOI: 10.1158/0008-5472.CAN-24-1359.


References
1.
Garcia-Esquinas E, Pollan M, Tellez-Plaza M, Francesconi K, Goessler W, Guallar E . Cadmium exposure and cancer mortality in a prospective cohort: the strong heart study. Environ Health Perspect. 2014; 122(4):363-70. PMC: 3984227. DOI: 10.1289/ehp.1306587. View

2.
Harmon M, Lewis J, Miller C, Hoover J, Ali A, Shuey C . Residential proximity to abandoned uranium mines and serum inflammatory potential in chronically exposed Navajo communities. J Expo Sci Environ Epidemiol. 2017; 27(4):365-371. PMC: 5781233. DOI: 10.1038/jes.2016.79. View

3.
Zhou X, Sun X, Cooper K, Wang F, Liu K, Hudson L . Arsenite interacts selectively with zinc finger proteins containing C3H1 or C4 motifs. J Biol Chem. 2011; 286(26):22855-63. PMC: 3123053. DOI: 10.1074/jbc.M111.232926. View

4.
Parkinson A, Hennessy T, Bulkow L, Smith H . The Alaska Area Specimen Bank: a tribal-federal partnership to maintain and manage a resource for health research. Int J Circumpolar Health. 2013; 72:20607. PMC: 3629262. DOI: 10.3402/ijch.v72i0.20607. View

5.
Liu J, Lewis G . Environmental toxicity and poor cognitive outcomes in children and adults. J Environ Health. 2014; 76(6):130-8. PMC: 4247328. View