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Paracentral Acute Middle Maculopathy: Precursor to Macular Thinning in Sickle Cell Retinopathy

Overview
Journal BMJ Case Rep
Specialty General Medicine
Date 2017 Apr 28
PMID 28446442
Citations 5
Authors
Syed Amal Hussnain
Patrick A Coady
Kathleen M Stoessel
Affiliations
Soon will be listed here.
Abstract

We present a case of paracentral acute middle maculopathy (PAMM) in a patient with sickle cell disease (SCD). Though gradual capillary loss may contribute to pathophysiology of sickle cell retinopathy as well, our case suggests that PAMM may be the precursor lesion to macular thinning commonly observed in patients with SCD. In addition, fluorescein angiography may be unable to detect these acute vascular events occurring at the deep capillary plexus.

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Transient vision loss associated with paracentral acute middle maculopathy detected on multi-modal imaging.

Sengillo J, Zhang L, Sridhar J, Flynn Jr H, Schwartz S Am J Ophthalmol Case Rep. 2021; 24:101195.

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[Maculopathy in sickle cell disease].

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Multifocal electroretinogram findings in sickle cell maculopathy.

Beral L, Romana M, Lemonne N, Garnier Y, Billaud M, Acomat M Eye (Lond). 2019; 33(12):1939-1945.

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Hemoglobin level and macular thinning in sickle cell disease.

Hussnain S, Coady P, Slade M, Carbonella J, Pashankar F, Adelman R Clin Ophthalmol. 2019; 13:627-632.

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