» Articles » PMID: 28442565

Mind the Magnesium, in Dantrolene Suppression of Malignant Hyperthermia

Overview
Specialty Science
Date 2017 Apr 27
PMID 28442565
Citations 3
Authors
Affiliations
Soon will be listed here.
Citing Articles

Ryanodine Receptor 1-Related Myopathies: Diagnostic and Therapeutic Approaches.

Lawal T, Todd J, Meilleur K Neurotherapeutics. 2018; 15(4):885-899.

PMID: 30406384 PMC: 6277304. DOI: 10.1007/s13311-018-00677-1.


Junctional membrane Ca dynamics in human muscle fibers are altered by malignant hyperthermia causative RyR mutation.

Cully T, Choi R, Bjorksten A, Stephenson D, Murphy R, Launikonis B Proc Natl Acad Sci U S A. 2018; 115(32):8215-8220.

PMID: 30038012 PMC: 6094124. DOI: 10.1073/pnas.1800490115.


Dantrolene : From Malignant Hyperthermia to Alzheimer's Disease.

Shi Y, Wang Y, Wei H CNS Neurol Disord Drug Targets. 2018; 18(9):668-676.

PMID: 29921212 PMC: 7754833. DOI: 10.2174/1871527317666180619162649.

References
1.
Diaz-Sylvester P, Porta M, Copello J . Halothane modulation of skeletal muscle ryanodine receptors: dependence on Ca2+, Mg2+, and ATP. Am J Physiol Cell Physiol. 2008; 294(4):C1103-12. PMC: 2465464. DOI: 10.1152/ajpcell.90642.2007. View

2.
Westerblad H, Allen D . Myoplasmic free Mg2+ concentration during repetitive stimulation of single fibres from mouse skeletal muscle. J Physiol. 1992; 453:413-34. PMC: 1175565. DOI: 10.1113/jphysiol.1992.sp019236. View

3.
Harrison G . Control of the malignant hyperpyrexic syndrome in MHS swine by dantrolene sodium. Br J Anaesth. 1975; 47(1):62-5. DOI: 10.1093/bja/47.1.62. View

4.
Monnier N, Procaccio V, STIEGLITZ P, Lunardi J . Malignant-hyperthermia susceptibility is associated with a mutation of the alpha 1-subunit of the human dihydropyridine-sensitive L-type voltage-dependent calcium-channel receptor in skeletal muscle. Am J Hum Genet. 1997; 60(6):1316-25. PMC: 1716149. DOI: 10.1086/515454. View

5.
Ellis K, BRYANT S . Excitation-contraction uncoupling in skeletal muscle by dantrolene sodium. Naunyn Schmiedebergs Arch Pharmacol. 1972; 274(1):107-9. DOI: 10.1007/BF00501011. View